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Gene

IL18

interleukin 18

Summary

Cytogenetic location
11q23.1
Coordinates
Chromosome 11: 112,143,260–112,164,094 (GRCh38)
Exons
6 exons across 20.8 kb
Protein
193 amino acids
Also known as
IGIF, IL1F4, IL-1g, IL-18
MANE Select transcript
ENST00000280357.12NM_001562.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads IL18 yet. The test sequences your whole genome, so your data includes it all the same.

How IL18 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 11, with a bracket where IL18 sits. IL18 and 21 genes near it on chromosome 11, from 111,653,677 to 112,653,676.Chromosome 1111q23.1p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q25111.8 Mb112 Mb112.2 Mb112.4 Mb112.6 MbSIK2: 111,602,383–111,730,855, forward strandSIK2PPP2R1B: 111,726,908–111,766,713, reverse strandPPP2R1BALG9: 111,782,195–111,872,405, reverse strand: 111,786,286–111,879,425, reverse strandFDXACB1: 111,873,947–111,881,243, reverse strandCFAP68: 111,878,935–111,885,975, forward strandCRYAB: 111,908,239–111,923,722, reverse strandCRYABHSPB2: 111,912,159–111,915,098, forward strandHSPB2-C11orf52: 111,912,736–111,926,871, forward strandHSPB2-C11orf52C11orf52: 111,918,032–111,926,873, forward strandC11orf52DIXDC1: 111,927,144–112,023,091, forward strandDIXDC1DLAT: 112,025,033–112,064,404, forward strandDLATPIH1D2: 112,052,485–112,074,274, reverse strandNKAPD1: 112,074,086–112,085,152, forward strandNKAPD1TIMM8B: 112,082,730–112,086,799, reverse strandTIMM8BSDHD: 112,086,361–112,120,016, forward strandSDHD: 112,086,903–112,193,805, forward strandIL18: 112,143,260–112,164,094, reverse strandIL18TEX12: 112,167,313–112,173,057, forward strandTEX12BCO2: 112,175,472–112,225,895, forward strandBCO2PTS: 112,226,059–112,270,449, forward strandPTSPLET1: 112,248,153–112,260,860, reverse strandPLET1Diagram of IL18: 6 exons on the reverse strand of chromosome 11Exon 6: 112,143,260–112,143,817, 558 basesExon 5: 112,148,603–112,148,736, 134 basesExon 4: 112,150,072–112,150,206, 135 basesExon 3: 112,153,592–112,153,603, 12 basesExon 2: 112,154,975–112,155,061, 87 basesExon 1: 112,163,906–112,164,094, 189 bases6543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.1 kb of the gene's 20.8 kb; 582 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). IL18 gene: interleukin 18. Retrieved 17 October 2026, from https://dantelabs.com/genes/il18

Vancouver

Dante Labs. IL18 gene: interleukin 18 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/il18

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