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Gene

HROB

homologous recombination factor with OB-fold

Summary

Cytogenetic location
17q21.31
Coordinates
Chromosome 17: 44,141,930–44,162,476 (GRCh38)
Exons
10 exons across 20.5 kb
Protein
646 amino acids
Also known as
MGC3130, MCM8IP
Previous symbols
C17orf53
MANE Select transcript
ENST00000585683.6NM_001171251.3
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads HROB yet. The test sequences your whole genome, so your data includes it all the same.

How HROB is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where HROB sits. HROB and 26 genes near it on chromosome 17, from 43,652,203 to 44,652,202.Chromosome 1717q21.31p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.343.8 Mb44 Mb44.2 Mb44.4 Mb44.6 MbMEOX1: 43,640,072–43,661,929, reverse strandMEOX1SOST: 43,753,738–43,758,791, reverse strandSOSTDUSP3: 43,763,629–43,779,000, reverse strandDUSP3CFAP97D1: 43,780,426–43,787,620, forward strandCFAP97D1MPP3: 43,800,795–43,833,203, reverse strandMPP3CD300LG: 43,847,114–43,863,639, forward strandCD300LGMPP2: 43,875,352–43,909,711, reverse strandMPP2PPY: 43,940,804–43,952,444, reverse strandPPYPYY: 43,952,733–44,004,469, reverse strandPYYNAGS: 44,004,581–44,011,213, forward strandNAGSTMEM101: 44,008,986–44,023,946, reverse strandTMEM101LSM12: 44,033,931–44,067,619, reverse strandLSM12G6PC3: 44,070,620–44,094,678, forward strandG6PC3HDAC5: 44,076,746–44,123,702, reverse strandHDAC5HROB: 44,141,930–44,162,476, forward strandHROBASB16: 44,170,447–44,179,373, forward strandASB16TMUB2: 44,186,955–44,191,931, forward strandTMUB2ATXN7L3: 44,191,804–44,200,961, reverse strandATXN7L3UBTF: 44,205,033–44,221,626, reverse strandUBTFSLC4A1: 44,248,390–44,268,162, reverse strandSLC4A1RUNDC3A: 44,307,945–44,318,675, forward strandRUNDC3ASLC25A39: 44,316,821–44,326,639, reverse strandSLC25A39GRN: 44,345,108–44,353,106, forward strandGRNFAM171A2: 44,353,215–44,363,875, reverse strandFAM171A2ITGA2B: 44,372,177–44,389,649, reverse strandITGA2BGPATCH8: 44,395,281–44,503,639, reverse strandGPATCH8FZD2: 44,557,484–44,561,262, forward strandFZD2Diagram of HROB: 10 exons on the forward strand of chromosome 17Exon 1: 44,141,930–44,142,145, 216 basesExon 2: 44,145,203–44,145,253, 51 basesExon 3: 44,147,858–44,149,027, 1,170 basesExon 4: 44,150,961–44,151,044, 84 basesExon 5: 44,152,637–44,152,777, 141 basesExon 6: 44,154,556–44,154,664, 109 basesExon 7: 44,154,853–44,154,938, 86 basesExon 8: 44,155,286–44,155,411, 126 basesExon 9: 44,157,833–44,157,941, 109 basesExon 10: 44,161,871–44,162,476, 606 bases12468105′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.7 kb of the gene's 20.5 kb; 1,941 of those bases code for the protein.

Traits linked to HROB

The Human Phenotype Ontology lists these as features of the rare conditions HROB can cause. Each trait's page lists the other genes linked to it.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). HROB gene: homologous recombination factor with OB-fold. Retrieved 17 October 2026, from https://dantelabs.com/genes/hrob

Vancouver

Dante Labs. HROB gene: homologous recombination factor with OB-fold [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/hrob

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