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Gene

GSTZ1

glutathione S-transferase zeta 1

Summary

Cytogenetic location
14q24.3
Coordinates
Chromosome 14: 77,321,036–77,331,597 (GRCh38)
Exons
9 exons across 10.6 kb
Protein
216 amino acids
Also known as
GSTZ1-1, MAAI, MAI
MANE Select transcript
ENST00000216465.10NM_145870.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GSTZ1 yet. The test sequences your whole genome, so your data includes it all the same.

How GSTZ1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 14, with a bracket where GSTZ1 sits. GSTZ1 and 19 genes near it on chromosome 14, from 76,826,317 to 77,826,316.Chromosome 1414q24.3p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.3377 Mb77.2 Mb77.4 Mb77.6 Mb77.8 MbLRRC74A: 76,826,372–76,870,304, forward strandLRRC74AIRF2BPL: 77,024,543–77,028,708, reverse strandIRF2BPLCIPC: 77,098,126–77,117,287, forward strandCIPC: 77,098,311–77,225,462, forward strandTMEM63C: 77,116,568–77,259,498, forward strandTMEM63CZDHHC22: 77,131,266–77,143,032, reverse strandZDHHC22NGB: 77,265,483–77,271,211, reverse strandNGBPOMT2: 77,274,956–77,320,898, reverse strandPOMT2GSTZ1: 77,321,036–77,331,597, forward strandGSTZ1TMED8: 77,335,024–77,377,348, reverse strandTMED8SAMD15: 77,376,689–77,392,372, forward strandSAMD15NOXRED1: 77,394,021–77,423,523, reverse strandNOXRED1VIPAS39: 77,426,674–77,457,952, reverse strandVIPAS39AHSA1: 77,457,743–77,469,482, forward strandAHSA1ISM2: 77,474,394–77,499,408, reverse strandISM2SPTLC2: 77,505,997–77,616,781, reverse strandSPTLC2ALKBH1: 77,672,401–77,708,038, reverse strandALKBH1SLIRP: 77,708,045–77,761,104, forward strandSLIRPSNW1: 77,709,019–77,761,207, reverse strandSNW1ADCK1: 77,800,059–77,937,188, forward strandADCK1Diagram of GSTZ1: 9 exons on the forward strand of chromosome 14Exon 3: 1 known disease-causing siteExon 5: 1 known disease-causing siteExon 1: 77,321,036–77,321,183, 148 basesExon 2: 77,324,870–77,324,921, 52 basesExon 3: 77,326,838–77,326,905, 68 basesExon 4: 77,327,472–77,327,552, 81 basesExon 5: 77,327,912–77,328,037, 126 basesExon 6: 77,329,123–77,329,201, 79 basesExon 7: 77,329,755–77,329,807, 53 basesExon 8: 77,330,310–77,330,359, 50 basesExon 9: 77,331,069–77,331,597, 529 bases1234567895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.2 kb of the gene's 10.6 kb; 651 of those bases code for the protein.

How a genome test reads GSTZ1

4

positions in GSTZ1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 10.6 kb of GSTZ1, introns included, not only the 1.2 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). GSTZ1 gene: glutathione S-transferase zeta 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/gstz1

Vancouver

Dante Labs. GSTZ1 gene: glutathione S-transferase zeta 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/gstz1

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