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Gene

GRK2

G protein-coupled receptor kinase 2

Summary

Cytogenetic location
11q13.2
Coordinates
Chromosome 11: 67,266,473–67,286,556 (GRCh38)
Exons
21 exons across 20.1 kb
Protein
689 amino acids
Also known as
BARK1
Previous symbols
ADRBK1
MANE Select transcript
ENST00000308595.10NM_001619.5
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads GRK2 yet. The test sequences your whole genome, so your data includes it all the same.

How GRK2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 11, with a bracket where GRK2 sits. GRK2 and 33 genes near it on chromosome 11, from 66,776,515 to 67,776,514.Chromosome 1111q13.2p15.5p15.4p15.3p15.2p15.1p14.3p14.2p14.1p13p12p11.2p11.12p11.11q11q12.1q12.2q12.3q13.1q13.2q13.3q13.4q13.5q14.1q14.2q14.3q21q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q2566.8 Mb67 Mb67.2 Mb67.4 Mb67.6 MbTOP6BL: 66,744,451–66,843,516, forward strandTOP6BLRCE1: 66,842,835–66,848,159, forward strandRCE1PC: 66,848,208–66,958,524, reverse strandPCLRFN4: 66,856,546–66,860,475, forward strandLRFN4C11orf86: 66,975,272–66,977,009, forward strandC11orf86SYT12: 67,006,772–67,051,110, forward strandSYT12RHOD: 67,056,608–67,072,044, forward strandRHODKDM2A: 67,119,247–67,258,082, forward strandKDM2AGRK2: 67,266,473–67,286,556, forward strandGRK2ANKRD13D: 67,288,655–67,302,486, forward strandANKRD13DSSH3: 67,303,478–67,312,608, forward strandSSH3RAD9A: 67,317,871–67,398,412, forward strandRAD9APOLD4: 67,345,400–67,356,972, reverse strandPOLD4: 67,351,572–67,373,584, reverse strandCLCF1: 67,364,168–67,374,301, reverse strandCLCF1PPP1CA: 67,398,176–67,421,183, reverse strandPPP1CATBC1D10C: 67,398,454–67,410,092, forward strandCARNS1: 67,414,968–67,425,613, forward strandRPS6KB2: 67,428,442–67,435,414, forward strandRPS6KB2PTPRCAP: 67,435,510–67,437,682, reverse strandCORO1B: 67,435,510–67,443,828, reverse strandCORO1BGPR152: 67,451,301–67,452,729, reverse strandCABP4: 67,452,406–67,461,752, forward strandTMEM134: 67,461,710–67,469,291, reverse strandAIP: 67,468,174–67,492,034, forward strandPITPNM1: 67,491,075–67,506,263, reverse strandCDK2AP2: 67,506,490–67,508,701, reverse strandCDK2AP2CABP2: 67,518,912–67,524,517, reverse strandCABP2GSTP1: 67,583,523–67,592,110, forward strandGSTP1NDUFV1: 67,605,653–67,612,554, forward strandNDUFV1NUDT8: 67,627,937–67,630,112, reverse strandNUDT8TBX10: 67,631,303–67,639,767, reverse strandTBX10ACY3: 67,642,551–67,650,900, reverse strandACY3ALDH3B2: 67,662,155–67,681,224, reverse strandDiagram of GRK2: 21 exons on the forward strand of chromosome 11Exon 1: 67,266,473–67,266,812, 340 basesExon 2: 67,277,272–67,277,348, 77 basesExon 3: 67,279,200–67,279,273, 74 basesExon 4: 67,279,418–67,279,519, 102 basesExon 5: 67,279,626–67,279,700, 75 basesExon 6: 67,279,839–67,279,900, 62 basesExon 7: 67,280,732–67,280,783, 52 basesExon 8: 67,281,093–67,281,184, 92 basesExon 9: 67,281,459–67,281,558, 100 basesExon 10: 67,281,650–67,281,728, 79 basesExon 11: 67,281,822–67,281,952, 131 basesExon 12: 67,282,271–67,282,365, 95 basesExon 13: 67,282,435–67,282,542, 108 basesExon 14: 67,282,752–67,282,818, 67 basesExon 15: 67,283,128–67,283,228, 101 basesExon 16: 67,283,707–67,283,773, 67 basesExon 17: 67,283,854–67,283,949, 96 basesExon 18: 67,284,211–67,284,373, 163 basesExon 19: 67,284,847–67,284,983, 137 basesExon 20: 67,285,075–67,285,188, 114 basesExon 21: 67,285,286–67,286,556, 1,271 bases12468101214161820215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.4 kb of the gene's 20.1 kb; 2,070 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). GRK2 gene: G protein-coupled receptor kinase 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/grk2

Vancouver

Dante Labs. GRK2 gene: G protein-coupled receptor kinase 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/grk2

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