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Gene

EME1

essential meiotic structure-specific endonuclease 1

Summary

Cytogenetic location
17q21.33
Coordinates
Chromosome 17: 50,373,229–50,381,483 (GRCh38)
Exons
9 exons across 8.3 kb
Protein
570 amino acids
Also known as
FLJ31364, MMS4L, SLX2A
MANE Select transcript
ENST00000338165.9NM_152463.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads EME1 yet. The test sequences your whole genome, so your data includes it all the same.

How EME1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 17, with a bracket where EME1 sits. EME1 and 25 genes near it on chromosome 17, from 49,877,356 to 50,877,355.Chromosome 1717q21.33p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.350 Mb50.2 Mb50.4 Mb50.6 Mb50.8 MbDLX4: 49,968,588–49,974,959, forward strandDLX4DLX3: 49,990,005–49,995,224, reverse strandDLX3ITGA3: 50,055,968–50,090,933, forward strandITGA3PDK2: 50,094,737–50,120,276, forward strandPDK2SAMD14: 50,110,040–50,130,160, reverse strandSAMD14PPP1R9B: 50,133,732–50,151,020, reverse strandPPP1R9BSGCA: 50,164,214–50,175,935, forward strandSGCACOL1A1: 50,184,101–50,201,704, reverse strandCOL1A1TMEM92: 50,271,406–50,281,916, forward strandTMEM92XYLT2: 50,346,080–50,363,138, forward strandXYLT2MRPL27: 50,367,293–50,373,207, reverse strandMRPL27EME1: 50,373,229–50,381,483, forward strandEME1LRRC59: 50,375,059–50,398,227, reverse strandLRRC59ACSF2: 50,426,158–50,474,845, forward strandACSF2CHAD: 50,464,478–50,468,976, reverse strandCHADRSAD1: 50,478,770–50,486,371, forward strandRSAD1MYCBPAP: 50,508,409–50,531,501, forward strandMYCBPAPEPN3: 50,532,543–50,543,750, forward strandEPN3SPATA20: 50,543,058–50,558,366, forward strandSPATA20CACNA1G: 50,560,715–50,627,474, forward strandCACNA1GABCC3: 50,634,609–50,692,631, forward strandABCC3ANKRD40: 50,693,197–50,707,920, reverse strandANKRD40LUC7L3: 50,719,565–50,756,219, forward strandLUC7L3ANKRD40CL: 50,760,960–50,767,570, reverse strandANKRD40CLWFIKKN2: 50,834,650–50,842,353, forward strandWFIKKN2TOB1: 50,861,311–50,867,978, reverse strandTOB1Diagram of EME1: 9 exons on the forward strand of chromosome 17Exon 1: 50,373,229–50,373,277, 49 basesExon 2: 50,375,185–50,375,983, 799 basesExon 3: 50,376,066–50,376,193, 128 basesExon 4: 50,378,595–50,378,681, 87 basesExon 5: 50,378,774–50,378,895, 122 basesExon 6: 50,379,107–50,379,224, 118 basesExon 7: 50,379,452–50,379,567, 116 basesExon 8: 50,380,312–50,380,501, 190 basesExon 9: 50,380,763–50,381,483, 721 bases1234567895′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.3 kb of the gene's 8.3 kb; 1,713 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). EME1 gene: essential meiotic structure-specific endonuclease 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/eme1

Vancouver

Dante Labs. EME1 gene: essential meiotic structure-specific endonuclease 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/eme1

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