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Gene

TOB1

transducer of ERBB2, 1

Summary

Cytogenetic location
17q21.33
Coordinates
Chromosome 17: 50,862,223–50,866,354 (GRCh38)
Exons
2 exons across 4.1 kb
Protein
345 amino acids
Also known as
TOB, TROB, APRO5
Previous symbols
TROB1
MANE Select transcript
ENST00000499247.3NM_005749.4
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TOB1 yet. The test sequences your whole genome, so your data includes it all the same.

How TOB1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 17, with a bracket where TOB1 sits. TOB1 and 21 genes near it on chromosome 17, from 50,364,289 to 51,364,288.Chromosome 1717q21.33p13.3p13.2p13.1p12p11.2p11.1q11.1q11.2q12q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.350.4 Mb50.6 Mb50.8 Mb51 Mb51.2 MbMRPL27: 50,367,293–50,373,207, reverse strandMRPL27EME1: 50,373,215–50,383,858, forward strandEME1LRRC59: 50,375,059–50,398,227, reverse strandLRRC59ACSF2: 50,426,158–50,474,845, forward strandACSF2CHAD: 50,464,478–50,468,976, reverse strandCHADRSAD1: 50,478,770–50,486,371, forward strandRSAD1MYCBPAP: 50,508,409–50,531,501, forward strandMYCBPAPEPN3: 50,532,543–50,543,750, forward strandEPN3SPATA20: 50,543,058–50,558,366, forward strandSPATA20CACNA1G: 50,560,715–50,627,474, forward strandCACNA1GABCC3: 50,634,609–50,692,631, forward strandABCC3ANKRD40: 50,693,197–50,707,920, reverse strandANKRD40LUC7L3: 50,719,565–50,756,219, forward strandLUC7L3ANKRD40CL: 50,760,960–50,767,570, reverse strandANKRD40CLWFIKKN2: 50,834,650–50,842,353, forward strandWFIKKN2TOB1: 50,862,223–50,866,354, reverse strandTOB1SPAG9: 50,962,174–51,120,926, reverse strandSPAG9NME1: 51,152,949–51,162,737, forward strandNME1NME1-NME2: 51,153,590–51,171,744, forward strandNME1-NME2NME2: 51,163,013–51,184,297, forward strandNME2MBTD1: 51,177,419–51,261,114, reverse strandMBTD1UTP18: 51,260,477–51,297,936, forward strandUTP18Diagram of TOB1: 2 exons on the reverse strand of chromosome 17Exon 2: 50,862,223–50,864,163, 1,941 basesExon 1: 50,866,058–50,866,354, 297 bases215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.2 kb of the gene's 4.1 kb; 1,038 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TOB1 gene: transducer of ERBB2, 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/tob1

Vancouver

Dante Labs. TOB1 gene: transducer of ERBB2, 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tob1

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