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Gene

ECE2

endothelin converting enzyme 2

Summary

Cytogenetic location
3q27.1
Coordinates
Chromosome 3: 184,276,022–184,293,031 (GRCh38)
Exons
19 exons across 17 kb
Protein
765 amino acids
Also known as
KIAA0604, MGC2408
MANE Select transcript
ENST00000404464.8NM_001100121.2
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads ECE2 yet. The test sequences your whole genome, so your data includes it all the same.

How ECE2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 3, with a bracket where ECE2 sits. ECE2 and 26 genes near it on chromosome 3, from 183,784,527 to 184,784,526.Chromosome 33q27.1p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q29183.8 Mb184 Mb184.2 Mb184.4 Mb184.6 MbYEATS2: 183,697,748–183,812,809, forward strandYEATS2: 183,815,568–183,884,889, reverse strandMAP6D1: 183,815,881–183,825,612, reverse strandMAP6D1PARL: 183,826,489–183,884,933, reverse strandPARLABCC5: 183,919,934–184,018,307, reverse strandABCC5HTR3D: 184,031,544–184,039,369, forward strandHTR3DHTR3C: 184,053,047–184,060,673, forward strandHTR3CHTR3E: 184,097,064–184,106,995, forward strandHTR3EEIF2B5: 184,134,986–184,146,127, forward strandEIF2B5DVL3: 184,155,159–184,173,616, forward strandDVL3AP2M1: 184,174,689–184,184,214, forward strandAP2M1ABCF3: 184,186,095–184,194,451, forward strandABCF3VWA5B2: 184,228,996–184,242,342, forward strandALG3: 184,242,301–184,249,571, reverse strandALG3EEF1AKMT4: 184,249,609–184,258,759, forward strandEEF1AKMT4-ECE2: 184,249,695–184,293,031, forward strandEEF1AKMT4-ECE2CAMK2N2: 184,259,213–184,261,602, reverse strandCAMK2N2ECE2: 184,276,022–184,293,031, forward strandECE2PSMD2: 184,299,157–184,309,054, forward strandPSMD2EIF4G1: 184,314,490–184,335,358, forward strandFAM131A: 184,335,916–184,348,421, forward strandFAM131ACLCN2: 184,346,185–184,363,274, reverse strandPOLR2H: 184,360,856–184,368,596, forward strandPOLR2HTHPO: 184,367,389–184,381,968, reverse strandTHPOCHRD: 184,379,381–184,390,736, forward strandEPHB3: 184,561,751–184,582,408, forward strandEPHB3MAGEF1: 184,708,749–184,712,073, reverse strandMAGEF1Diagram of ECE2: 19 exons on the forward strand of chromosome 3Exon 1: 184,276,022–184,276,192, 171 basesExon 2: 184,276,481–184,276,567, 87 basesExon 3: 184,276,892–184,277,027, 136 basesExon 4: 184,277,251–184,277,466, 216 basesExon 5: 184,277,925–184,278,049, 125 basesExon 6: 184,278,167–184,278,313, 147 basesExon 7: 184,278,492–184,278,557, 66 basesExon 8: 184,283,785–184,283,973, 189 basesExon 9: 184,284,963–184,285,105, 143 basesExon 10: 184,285,478–184,285,592, 115 basesExon 11: 184,287,837–184,287,947, 111 basesExon 12: 184,289,437–184,289,535, 99 basesExon 13: 184,289,641–184,289,718, 78 basesExon 14: 184,290,255–184,290,358, 104 basesExon 15: 184,290,557–184,290,667, 111 basesExon 16: 184,290,793–184,290,860, 68 basesExon 17: 184,291,040–184,291,230, 191 basesExon 18: 184,291,344–184,291,439, 96 basesExon 19: 184,292,062–184,293,031, 970 bases124681012141618195′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.2 kb of the gene's 17 kb; 2,298 of those bases code for the protein.

Sequencing ECE2

2Low

How hard ECE2 is to sequence with short reads, out of 100

  • Mappability0%
  • Homology0%
  • Repeats0.5%
  • GC content16%
  • Reference coverage0%

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). ECE2 gene: endothelin converting enzyme 2. Retrieved 17 October 2026, from https://dantelabs.com/genes/ece2

Vancouver

Dante Labs. ECE2 gene: endothelin converting enzyme 2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ece2

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