Skip to content
Use your HSA or FSA funds

Gene

DOCK1

dedicator of cytokinesis 1

Summary

Cytogenetic location
10q26.2
Coordinates
Chromosome 10: 126,905,428–127,452,516 (GRCh38)
Exons
52 exons across 547.1 kb
Protein
1,886 amino acids
Also known as
DOCK180, ced5
MANE Select transcript
ENST00000623213.2NM_001290223.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DOCK1 yet. The test sequences your whole genome, so your data includes it all the same.

How DOCK1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Known disease-causing sites
  • Stretches short reads find hard
Chromosome 10, with a bracket where DOCK1 sits. DOCK1 and 7 genes near it on chromosome 10, from 126,358,339 to 127,999,605.Chromosome 1010q26.2p15.3p15.2p15.1p14p13p12.33p12.32p12.31p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.31q23.32q23.33q24.1q24.2q24.31q24.32q24.33q25.1q25.2q25.3q26.11q26.12q26.13q26.2q26.3126.4 Mb126.6 Mb126.8 Mb127 Mb127.2 Mb127.4 Mb127.6 Mb127.8 MbADAM12: 126,012,381–126,388,502, reverse strandADAM12C10orf90: 126,424,997–126,798,708, reverse strandC10orf90DOCK1: 126,905,428–127,452,516, forward strandDOCK1INSYN2A: 127,135,426–127,196,592, reverse strandINSYN2ANPS: 127,549,309–127,553,540, forward strandNPSFOXI2: 127,737,118–127,741,183, forward strandFOXI2CLRN3: 127,875,988–127,907,298, reverse strandCLRN3PTPRE: 127,906,800–128,085,856, forward strandPTPREDiagram of DOCK1: 52 exons on the forward strand of chromosome 10Exon 20: 1 known disease-causing siteExon 1: 126,905,428–126,905,563, 136 basesExon 2: 126,970,702–126,970,785, 84 basesExon 3: 126,977,948–126,977,988, 41 basesExon 4: 126,981,918–126,981,973, 56 basesExon 5: 126,987,521–126,987,617, 97 basesExon 6: 126,990,455–126,990,603, 149 basesExon 7: 126,996,748–126,996,883, 136 basesExon 8: 126,998,092–126,998,249, 158 basesExon 9: 126,999,354–126,999,435, 82 basesExon 10: 127,000,172–127,000,307, 136 basesExon 11: 127,008,732–127,008,804, 73 basesExon 12: 127,012,232–127,012,374, 143 basesExon 13: 127,018,710–127,018,835, 126 basesExon 14: 127,023,200–127,023,324, 125 basesExon 15: 127,024,685–127,024,783, 99 basesExon 16: 127,026,352–127,026,424, 73 basesExon 17: 127,031,650–127,031,753, 104 basesExon 18: 127,032,137–127,032,320, 184 basesExon 19: 127,037,719–127,037,816, 98 basesExon 20: 127,042,625–127,042,714, 90 basesExon 21: 127,043,064–127,043,164, 101 basesExon 22: 127,052,681–127,052,815, 135 basesExon 23: 127,061,668–127,061,776, 109 basesExon 24: 127,106,231–127,106,301, 71 basesExon 25: 127,110,248–127,110,354, 107 basesExon 26: 127,125,474–127,125,601, 128 basesExon 27: 127,127,669–127,127,764, 96 basesExon 28: 127,248,008–127,248,109, 102 basesExon 29: 127,257,335–127,257,429, 95 basesExon 30: 127,339,006–127,339,084, 79 basesExon 31: 127,343,646–127,343,746, 101 basesExon 32: 127,354,669–127,354,727, 59 basesExon 33: 127,362,064–127,362,212, 149 basesExon 34: 127,373,781–127,373,866, 86 basesExon 35: 127,374,058–127,374,214, 157 basesExon 36: 127,380,082–127,380,122, 41 basesExon 37: 127,381,278–127,381,368, 91 basesExon 38: 127,384,790–127,384,909, 120 basesExon 39: 127,403,055–127,403,144, 90 basesExon 40: 127,404,325–127,404,429, 105 basesExon 41: 127,409,037–127,409,178, 142 basesExon 42: 127,409,313–127,409,391, 79 basesExon 43: 127,410,840–127,410,924, 85 basesExon 44: 127,415,152–127,415,238, 87 basesExon 45: 127,418,365–127,418,541, 177 basesExon 46: 127,419,666–127,419,749, 84 basesExon 47: 127,425,874–127,426,011, 138 basesExon 48: 127,433,283–127,433,428, 146 basesExon 49: 127,439,027–127,439,225, 199 basesExon 50: 127,444,126–127,444,279, 154 basesExon 51: 127,447,394–127,447,545, 152 basesExon 52: 127,451,332–127,452,516, 1,185 bases12040525′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.8 kb of the gene's 547.1 kb; 5,661 of those bases code for the protein.

How a genome test reads DOCK1

1

position in DOCK1 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 547.1 kb of DOCK1, introns included, not only the 6.8 kb of exons.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). DOCK1 gene: dedicator of cytokinesis 1. Retrieved 17 October 2026, from https://dantelabs.com/genes/dock1

Vancouver

Dante Labs. DOCK1 gene: dedicator of cytokinesis 1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/dock1

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test