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Gene

DEFB4B

defensin beta 4B

Summary

Cytogenetic location
8p23.1
Coordinates
Chromosome 8: 7,414,855–7,416,863 (GRCh38)
Exons
2 exons across 2 kb
Protein
64 amino acids
Previous symbols
DEFB4P
MANE Select transcript
ENST00000318157.3NM_001205266.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DEFB4B yet. The test sequences your whole genome, so your data includes it all the same.

How DEFB4B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 8, with a bracket where DEFB4B sits. DEFB4B and 42 genes near it on chromosome 8, from 6,915,859 to 7,915,858.Chromosome 88p23.1p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.37 Mb7.2 Mb7.4 Mb7.6 Mb7.8 MbDEFA6: 6,924,697–6,926,076, reverse strandDEFA6DEFA4: 6,935,820–6,938,313, reverse strandDEFA4DEFA1: 6,977,649–6,980,094, reverse strandDEFA1DEFA1B: 6,996,766–6,999,206, reverse strandDEFA1BDEFA3: 7,015,868–7,018,359, reverse strandDEFA3DEFA5: 7,055,251–7,056,740, reverse strandDEFA5FAM90A15: 7,256,904–7,259,914, forward strandFAM90A15FAM90A3: 7,264,526–7,267,536, forward strandFAM90A3FAM90A13: 7,279,770–7,282,780, forward strandFAM90A5: 7,287,392–7,290,402, forward strandFAM90A20: 7,295,014–7,298,024, forward strandFAM90A20DEFB109B: 7,312,722–7,320,096, forward strandUSP17L1: 7,332,387–7,333,979, forward strandUSP17L1USP17L4: 7,337,115–7,338,707, forward strandUSP17L4ZNF705G: 7,355,517–7,385,558, reverse strandZNF705GDEFB108C: 7,373,114–7,377,500, forward strandDEFB108CDEFB4B: 7,414,855–7,416,863, reverse strandDEFB4BDEFB103B: 7,428,888–7,430,348, reverse strandDEFB103BSPAG11B: 7,442,684–7,463,674, reverse strandSPAG11BDEFB104B: 7,470,308–7,475,082, reverse strandDEFB104BDEFB106B: 7,482,504–7,486,400, reverse strandDEFB105B: 7,487,679–7,489,593, forward strandDEFB107B: 7,495,911–7,509,311, forward strandPRR23D1: 7,539,627–7,542,450, forward strandPRR23D1FAM90A7: 7,556,700–7,559,712, reverse strandFAM90A7FAM90A22: 7,571,995–7,575,006, reverse strandFAM90A22FAM90A23: 7,579,644–7,582,653, reverse strandFAM90A23FAM90A14: 7,715,443–7,718,453, forward strandFAM90A14FAM90A18: 7,723,091–7,726,101, forward strandFAM90A18FAM90A16: 7,730,739–7,733,749, forward strandFAM90A16FAM90A8: 7,738,387–7,741,396, forward strandFAM90A8FAM90A17: 7,746,034–7,749,044, forward strandFAM90A19: 7,751,570–7,756,692, forward strandFAM90A9: 7,761,330–7,764,340, forward strandFAM90A10: 7,766,902–7,772,547, forward strandPRR23D2: 7,778,591–7,781,413, reverse strandDEFB107A: 7,811,720–7,815,716, reverse strandDEFB107ADEFB105A: 7,821,004–7,823,880, reverse strandDEFB105ADEFB106A: 7,825,139–7,829,053, forward strandDEFB106ADEFB104A: 7,836,436–7,841,242, forward strandDEFB104ASPAG11A: 7,847,876–7,868,867, forward strandDEFB103A: 7,881,392–7,882,663, forward strandDEFB4A: 7,894,676–7,896,716, forward strandDEFB4ADiagram of DEFB4B: 2 exons on the reverse strand of chromosome 8Exon 2: 7,414,855–7,415,097, 243 basesExon 1: 7,416,770–7,416,863, 94 bases215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.3 kb of the gene's 2 kb; 195 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). DEFB4B gene: defensin beta 4B. Retrieved 17 October 2026, from https://dantelabs.com/genes/defb4b

Vancouver

Dante Labs. DEFB4B gene: defensin beta 4B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/defb4b

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