Skip to content
Use your HSA or FSA funds

Gene

DEFB4A

defensin beta 4A

Summary

Cytogenetic location
8p23.1
Coordinates
Chromosome 8: 7,894,677–7,896,716 (GRCh38)
Exons
2 exons across 2 kb
Protein
64 amino acids
Also known as
SAP1, HBD-2, DEFB-2
Previous symbols
DEFB102, DEFB2, DEFB4
MANE Select transcript
ENST00000302247.3NM_004942.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads DEFB4A yet. The test sequences your whole genome, so your data includes it all the same.

How DEFB4A is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 8, with a bracket where DEFB4A sits. DEFB4A and 34 genes near it on chromosome 8, from 7,395,697 to 8,395,696.Chromosome 88p23.1p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.37.4 Mb7.6 Mb7.8 Mb8 Mb8.2 MbDEFB4B: 7,414,855–7,416,863, reverse strandDEFB4BDEFB103B: 7,428,888–7,430,348, reverse strandSPAG11B: 7,442,684–7,463,674, reverse strandDEFB104B: 7,470,308–7,475,082, reverse strandDEFB106B: 7,482,504–7,486,400, reverse strandDEFB106BDEFB105B: 7,487,679–7,489,593, forward strandDEFB105BDEFB107B: 7,495,911–7,509,311, forward strandDEFB107BPRR23D1: 7,539,627–7,542,450, forward strandPRR23D1FAM90A7: 7,556,700–7,559,712, reverse strandFAM90A7FAM90A22: 7,571,995–7,575,006, reverse strandFAM90A22FAM90A23: 7,579,644–7,582,653, reverse strandFAM90A23FAM90A14: 7,715,443–7,718,453, forward strandFAM90A18: 7,723,091–7,726,101, forward strandFAM90A16: 7,730,739–7,733,749, forward strandFAM90A8: 7,738,387–7,741,396, forward strandFAM90A17: 7,746,034–7,749,044, forward strandFAM90A19: 7,751,570–7,756,692, forward strandFAM90A19FAM90A9: 7,761,330–7,764,340, forward strandFAM90A9FAM90A10: 7,766,902–7,772,547, forward strandFAM90A10PRR23D2: 7,778,591–7,781,413, reverse strandPRR23D2DEFB107A: 7,811,720–7,815,716, reverse strandDEFB105A: 7,821,004–7,823,880, reverse strandDEFB106A: 7,825,139–7,829,053, forward strandDEFB104A: 7,836,436–7,841,242, forward strandDEFB104ASPAG11A: 7,847,876–7,868,867, forward strandSPAG11ADEFB103A: 7,881,392–7,882,663, forward strandDEFB103ADEFB4A: 7,894,677–7,896,716, forward strandDEFB4AZNF705B: 7,926,337–7,952,413, forward strandZNF705BUSP17L8: 7,971,661–7,973,253, reverse strandUSP17L8USP17L3: 7,976,393–7,977,985, reverse strandUSP17L3DEFB109C: 7,990,270–7,997,645, reverse strandDEFB109CFAM90A11: 8,012,342–8,015,352, reverse strandFAM90A11FAM90A24: 8,019,988–8,022,998, reverse strandFAM90A12: 8,027,636–8,030,646, reverse strandPRAG1: 8,317,736–8,387,357, reverse strandPRAG1Diagram of DEFB4A: 2 exons on the forward strand of chromosome 8Exon 1: 7,894,677–7,894,770, 94 basesExon 2: 7,896,474–7,896,716, 243 bases125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.3 kb of the gene's 2 kb; 195 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). DEFB4A gene: defensin beta 4A. Retrieved 17 October 2026, from https://dantelabs.com/genes/defb4a

Vancouver

Dante Labs. DEFB4A gene: defensin beta 4A [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/defb4a

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test