Skip to content
Use your HSA or FSA funds
Sequence your genome (opens in a new tab)

Gene

CXorf65

chromosome X open reading frame 65

Summary

Cytogenetic location
Xq13.1
Coordinates
Chromosome X: 71,103,889–71,106,740 (GRCh38)
Exons
6 exons across 2.9 kb
Protein
183 amino acids
MANE Select transcript
ENST00000374251.6NM_001025265.3
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads CXorf65 yet. The test sequences your whole genome, so your data includes it all the same.

How CXorf65 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome X, with a bracket where CXorf65 sits. CXorf65 and 15 genes near it on chromosome X, from 70,605,315 to 71,605,314.Chromosome XXq13.1p22.33p22.32p22.31p22.2p22.13p22.12p22.11p21.3p21.2p21.1p11.4p11.3p11.23p11.22p11.21p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q23q24q25q26.1q26.2q26.3q27.1q27.2q27.3q2870.8 Mb71 Mb71.2 Mb71.4 Mb71.6 MbTEX11: 70,528,940–70,908,711, reverse strandTEX11SLC7A3: 70,925,556–70,931,149, reverse strandSLC7A3SNX12: 70,963,111–71,073,426, reverse strandSNX12FOXO4: 71,095,839–71,103,535, forward strandFOXO4CXorf65: 71,103,889–71,106,740, reverse strandCXorf65: 71,103,987–71,111,575, reverse strandIL2RG: 71,107,404–71,112,108, reverse strandIL2RGMED12: 71,118,543–71,144,103, forward strandNLGN3: 71,143,286–71,175,306, forward strandNLGN3GJB1: 71,212,811–71,225,519, forward strandGJB1ZMYM3: 71,239,617–71,255,269, reverse strandZMYM3NONO: 71,254,270–71,301,522, forward strandNONOITGB1BP2: 71,301,717–71,305,371, forward strandITGB1BP2TAF1: 71,366,129–71,532,374, forward strandTAF1OGT: 71,533,068–71,575,892, forward strandOGTGCNA: 71,578,436–71,613,590, forward strandGCNADiagram of CXorf65: 6 exons on the reverse strand of chromosome XExon 6: 71,103,889–71,104,112, 224 basesExon 5: 71,104,298–71,104,404, 107 basesExon 4: 71,104,769–71,104,837, 69 basesExon 3: 71,106,000–71,106,137, 138 basesExon 2: 71,106,340–71,106,426, 87 basesExon 1: 71,106,532–71,106,740, 209 bases6543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 0.8 kb of the gene's 2.9 kb; 552 of those bases code for the protein.

Sequencing CXorf65

0Easy

How hard CXorf65 is to sequence with short reads, out of 100

Almost all of CXorf65's exons sit where short reads map cleanly.

What adds to it: the share of CXorf65's exons in each kind of hard region

  • Mappability0%
  • Homology0%
  • Shared with chrY0%
  • Reference coverage0%
  • Repeats0%
  • GC content0%

A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scored

1

position in CXorf65 where ClinVar classes a change as pathogenic or likely pathogenic

None of them falls in a region short reads find hard.

A whole genome covers all 2.9 kb of CXorf65, introns included, not only the 0.8 kb of exons.

ClinVar pathogenic variants (1)

The CXorf65 variants ClinVar classifies pathogenic or likely pathogenic for any condition, reviewed by at least one submitter with criteria, and the most reviewed of them. It is ClinVar's public record of the gene, never a result.

  • Pathogenic 1
VariantConditionsClinVar classificationReview status
NM_000206.3(IL2RG):c.270-15A>G (opens in a new tab)T-B+ severe combined immunodeficiency due to gamma chain deficiencyPathogenic2 stars out of 4 criteria provided, multiple submitters, no conflicts

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • ClinVar and the GIAB stratifications: known disease-causing sites, and the regions short reads find hard.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
  • Data release 2026.10.19-9814e911.

Cite this page

APA

Dante Labs. (n.d.). CXorf65 gene: chromosome X open reading frame 65. Retrieved 19 October 2026, from https://dantelabs.com/genes/cxorf65

Vancouver

Dante Labs. CXorf65 gene: chromosome X open reading frame 65 [Internet]. [cited 19 October 2026]. Available from: https://dantelabs.com/genes/cxorf65

One test. A lifetime of answers.

From $449Free shipping · Results in 6–8 weeks

Get my Genome Test