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Gene

APLP1

amyloid beta precursor like protein 1

Summary

Cytogenetic location
19q13.12
Coordinates
Chromosome 19: 35,868,574–35,879,792 (GRCh38)
Exons
17 exons across 11.2 kb
Protein
651 amino acids
Also known as
APLP
MANE Select transcript
ENST00000221891.9NM_001024807.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads APLP1 yet. The test sequences your whole genome, so your data includes it all the same.

How APLP1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 19, with a bracket where APLP1 sits. APLP1 and 45 genes near it on chromosome 19, from 35,374,183 to 36,374,182.Chromosome 1919q13.12p13.3p13.2p13.13p13.12p13.11p12p11q11q12q13.11q13.12q13.13q13.2q13.31q13.32q13.33q13.41q13.42q13.4335.4 Mb35.6 Mb35.8 Mb36 Mb36.2 MbFFAR2: 35,443,907–35,451,767, forward strandFFAR2KRTDAP: 35,487,324–35,495,558, reverse strandDMKN: 35,497,220–35,513,704, reverse strandDMKNSBSN: 35,523,367–35,528,351, reverse strandSBSNGAPDHS: 35,533,455–35,545,319, forward strandGAPDHSTMEM147: 35,545,600–35,547,527, forward strandTMEM147ATP4A: 35,549,339–35,563,658, reverse strandATP4APMIS2: 35,586,161–35,587,296, forward strandPMIS2HAUS5: 35,612,735–35,625,355, forward strandHAUS5RBM42: 35,628,989–35,638,927, forward strandRBM42ETV2: 35,641,730–35,644,871, forward strandETV2COX6B1: 35,648,230–35,662,890, forward strandCOX6B1UPK1A: 35,666,516–35,678,481, forward strandUPK1AZBTB32: 35,704,558–35,717,048, forward strandKMT2B: 35,717,973–35,738,880, forward strandIGFLR1: 35,738,798–35,742,459, reverse strand: 35,739,252–35,745,432, reverse strandU2AF1L4: 35,742,464–35,745,460, reverse strandPSENEN: 35,745,070–35,747,519, forward strand: 35,745,678–35,754,519, forward strandLIN37: 35,748,361–35,754,519, forward strandHSPB6: 35,754,566–35,758,079, reverse strandHSPB6PROSER3: 35,758,143–35,771,398, forward strandPROSER3ARHGAP33: 35,774,532–35,788,822, forward strandARHGAP33PRODH2: 35,799,975–35,813,299, reverse strandPRODH2NPHS1: 35,825,372–35,869,287, reverse strandNPHS1KIRREL2: 35,851,369–35,867,145, forward strandKIRREL2APLP1: 35,868,574–35,879,792, forward strandAPLP1NFKBID: 35,887,129–35,902,303, reverse strandNFKBIDHCST: 35,899,017–35,904,377, forward strandHCSTTYROBP: 35,904,398–35,908,318, reverse strandLRFN3: 35,935,358–35,946,624, forward strandLRFN3SDHAF1: 35,995,188–35,996,312, forward strandSDHAF1SYNE4: 36,000,545–36,008,831, reverse strandSYNE4ALKBH6: 36,009,113–36,014,297, reverse strandALKBH6CLIP3: 36,014,660–36,033,343, reverse strandCLIP3THAP8: 36,033,393–36,054,739, reverse strandWDR62: 36,054,649–36,105,112, forward strandWDR62OVOL3: 36,111,116–36,113,711, forward strandOVOL3POLR2I: 36,111,817–36,115,213, reverse strandPOLR2ITBCB: 36,114,289–36,125,948, forward strandTBCBCAPNS1: 36,139,953–36,150,356, forward strandCAPNS1COX7A1: 36,150,287–36,152,699, reverse strandZNF565: 36,181,542–36,246,257, reverse strandZNF565ZNF146: 36,214,602–36,239,969, forward strandZNF146ZFP14: 36,334,453–36,379,208, reverse strandZFP14Diagram of APLP1: 17 exons on the forward strand of chromosome 19Exon 1: 35,868,574–35,868,783, 210 basesExon 2: 35,869,667–35,869,810, 144 basesExon 3: 35,870,896–35,871,028, 133 basesExon 4: 35,871,237–35,871,349, 113 basesExon 5: 35,871,612–35,871,745, 134 basesExon 6: 35,871,858–35,872,036, 179 basesExon 7: 35,872,483–35,872,613, 131 basesExon 8: 35,873,639–35,873,713, 75 basesExon 9: 35,874,504–35,874,662, 159 basesExon 10: 35,874,741–35,874,869, 129 basesExon 11: 35,876,517–35,876,616, 100 basesExon 12: 35,877,718–35,877,825, 108 basesExon 13: 35,878,082–35,878,108, 27 basesExon 14: 35,878,584–35,878,654, 71 basesExon 15: 35,878,890–35,878,952, 63 basesExon 16: 35,879,074–35,879,217, 144 basesExon 17: 35,879,343–35,879,792, 450 bases1246810121416175′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.4 kb of the gene's 11.2 kb; 1,956 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). APLP1 gene: amyloid beta precursor like protein 1. Retrieved 16 October 2026, from https://dantelabs.com/genes/aplp1

Vancouver

Dante Labs. APLP1 gene: amyloid beta precursor like protein 1 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/aplp1

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