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Gene

ANGPT2

angiopoietin 2

Summary

Cytogenetic location
8p23.1
Coordinates
Chromosome 8: 6,499,632–6,563,245 (GRCh38)
Exons
9 exons across 63.6 kb
Protein
495 amino acids
Also known as
Ang2
MANE Select transcript
ENST00000629816.3NM_001118887.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated report relevant to this gene

How ANGPT2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 8, with a bracket where ANGPT2 sits. ANGPT2 and 9 genes near it on chromosome 8, from 6,031,439 to 7,031,438.Chromosome 88p23.1p23.3p23.2p23.1p22p21.3p21.2p21.1p12p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.3q21.11q21.12q21.13q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.36.2 Mb6.4 Mb6.6 Mb6.8 Mb7 MbMCPH1: 6,406,592–6,648,508, forward strandMCPH1ANGPT2: 6,499,632–6,563,245, reverse strandANGPT2AGPAT5: 6,708,334–6,761,604, forward strandAGPAT5XKR5: 6,805,013–6,835,536, reverse strandXKR5DEFB1: 6,870,592–6,877,943, reverse strandDEFB1DEFA6: 6,924,697–6,926,076, reverse strandDEFA6DEFA4: 6,935,820–6,938,313, reverse strandDEFA4DEFA1: 6,977,649–6,980,094, reverse strandDEFA1DEFA1B: 6,996,766–6,999,206, reverse strandDEFA1BDEFA3: 7,015,868–7,018,359, reverse strandDEFA3Diagram of ANGPT2: 9 exons on the reverse strand of chromosome 8Exon 9: 6,499,632–6,503,261, 3,630 basesExon 8: 6,508,932–6,509,062, 131 basesExon 7: 6,513,678–6,513,844, 167 basesExon 6: 6,514,677–6,514,778, 102 basesExon 5: 6,519,864–6,519,991, 128 basesExon 4: 6,521,178–6,521,410, 233 basesExon 3: 6,527,555–6,527,676, 122 basesExon 2: 6,532,332–6,532,487, 156 basesExon 1: 6,562,647–6,563,245, 599 bases9864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.3 kb of the gene's 63.6 kb; 1,488 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • GenCC and ClinGen, released 2026-10-16: which conditions the gene is linked to, and how strongly.
  • The ACMG secondary findings list, SF v3.2.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

Cite this page

APA

Dante Labs. (n.d.). ANGPT2 gene: angiopoietin 2. Retrieved 16 October 2026, from https://dantelabs.com/genes/angpt2

Vancouver

Dante Labs. ANGPT2 gene: angiopoietin 2 [Internet]. [cited 16 October 2026]. Available from: https://dantelabs.com/genes/angpt2

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