Risk score · Immune & inflammatory
Lupus Polygenic Risk Score
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease where the immune system mistakenly attacks healthy tissues and organs.
A risk score adds up many common variants, each with a small effect, into an estimate of genetic predisposition. It is not a diagnosis.
Included in Premium and Premium + AI
How the score works
A polygenic score for Systemic lupus erythematosus
Genetic variants
- 57
Method
- Genomewide-significant variants (sourced from PMID:28509669)
Built from studies of
- European 100%
Evaluated in
- European 100%
Published
Reid S et al. (2019). High genetic risk score is associated with early disease onset, damage accrual and decreased survival in systemic lupus erythematosus. Ann Rheum Dis.
Limitations
- SLE is triggered by a mix of genetic, environmental, and hormonal factors.
Other immune & inflammatory risk scores
All conditions →One test. A lifetime of answers.
One kit, sent to your home. Your entire genome sequenced at the clinical standard used for diagnostic decisions. Physician-ready reports delivered to your Genome Manager in 6–8 weeks — permanent and updated as science advances.
Free shipping · Results in 6–8 weeks
Premium adds $99 per kit for the first year.
