Trait
Reduced circulating CH50 activity
A diminished activity of the classical complement pathway as measured by the assay for 50% haemolytic complement (CH50) activity of serum.
Summary
- Also called
- Decreased total hemolytic complement activity, Reduced CH50, Reduced circulating 50% hemolytic complement (CH50) activity, Reduced hemolytic complement activity
- Body system
- Abnormality of the immune system
Reference genomeGRCh38hg38
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Get my Genome Test5 genes linked to Reduced circulating CH50 activity
Changes in these genes cause rare conditions in which Reduced circulating CH50 activity is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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