Trait
Patchy palmoplantar hyperkeratosis
A focal type of palmoplantar keratoderma in which only certain areas of the palms and soles are affected.
Summary
- Also called
- Palmoplantar keratoderma, patchy, Patchy palmoplantar keratoderma
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test6 genes linked to Patchy palmoplantar hyperkeratosis
Changes in these genes cause rare conditions in which Patchy palmoplantar hyperkeratosis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| TRPV3transient receptor potential cation channel subfamily V member 3 | Always | In 1 condition |
| DSPdesmoplakin | Very often (80–99%) | In 1 condition |
| GJA1gap junction protein alpha 1 | Often (30–79%) | In 1 condition |
| GJB3gap junction protein beta 3 | Often (30–79%) | In 2 conditions |
| GJB4gap junction protein beta 4 | Often (30–79%) | In 1 condition |
| KDSR3-ketodihydrosphingosine reductase | Often (30–79%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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