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Trait

Myocardial necrosis

Irreversible damage to heart tissue (myocardium) due to lack of oxygen after a heart attack (myocardial infarction).

HPO HP:0001700

Summary

Body system
Abnormality of the cardiovascular system

4 genes linked to Myocardial necrosis

Changes in these genes cause rare conditions in which Myocardial necrosis is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
DNAJC21DnaJ heat shock protein family (Hsp40) member C21Not recordedIn 1 condition
LAMP2lysosome associated membrane protein 2Not recordedIn 1 condition
SBDSSBDS ribosome maturation factorNot recordedIn 1 condition
SRP54signal recognition particle 54Not recordedIn 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal myocardium morphology

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.16-c6eea6bf.

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