Trait

Keratinocyte vacuolization

Increased number of vacuoles (membrane-bound organelles that areempty of cytoplasm, lined with a membrane, and filled with fluid) in keratinocytes.

HPO HP:0034703

Also called: Keratinocyte vacuolation, Vacuolated keratinocytes
Body system: Abnormality of the integument

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library(jsonlite)

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page$trait$name

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1 gene linked to Keratinocyte vacuolization

Changes in these genes cause rare conditions in which Keratinocyte vacuolization is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
KRT10keratin 10	Always	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal keratinocyte morphology

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.17-8666dff2.

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