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Trait

Increased serum leptin

An increased concentration of leptin in the blood.

HPO HP:0031793

Summary

Also called
Elevated circulating leptin level
Body system
Abnormality of the endocrine system

3 condition reports read genes linked to this trait

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2 genes linked to Increased serum leptin

Changes in these genes cause rare conditions in which Increased serum leptin is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
ADCY3adenylate cyclase 3AlwaysIn 1 condition
MECP2methyl-CpG binding protein 2Sometimes (5–29%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal circulating leptin concentration

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.18-8b139e39.

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