{
  "url": "https://dantelabs.com/traits/increased-serum-leptin",
  "trait": {
    "bundleId": "2026.10.18-8b139e39",
    "release": "2026-09-01",
    "slug": "increased-serum-leptin",
    "id": "HP:0031793",
    "name": "Increased serum leptin",
    "definition": "An increased concentration of leptin in the blood.",
    "synonyms": [
      "Elevated circulating leptin level"
    ],
    "systems": [
      {
        "slug": "abnormality-of-the-endocrine-system",
        "name": "Abnormality of the endocrine system",
        "url": "https://dantelabs.com/traits/abnormality-of-the-endocrine-system"
      }
    ],
    "broader": [
      {
        "slug": "abnormal-circulating-leptin-concentration",
        "name": "Abnormal circulating leptin concentration",
        "url": "https://dantelabs.com/traits/abnormal-circulating-leptin-concentration"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "adcy3",
        "symbol": "ADCY3",
        "hgnc": "HGNC:234",
        "name": "adenylate cyclase 3",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/adcy3"
      },
      {
        "slug": "mecp2",
        "symbol": "MECP2",
        "hgnc": "HGNC:6990",
        "name": "methyl-CpG binding protein 2",
        "frequency": "occasional",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/mecp2"
      }
    ]
  }
}