Trait

Hyperextensible hand joints

The ability of the joints of the hand to move beyond their normal range of motion.

Body system: Abnormality of the musculoskeletal system

This page as data

Add .json to the page's address, or ask for application/json, to read it as JSON.

library(jsonlite)

url <- "https://dantelabs.com/traits/hyperextensible-hand-joints.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

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4 genes linked to Hyperextensible hand joints

Changes in these genes cause rare conditions in which Hyperextensible hand joints is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
MOCS3molybdenum cofactor synthesis 3	Always	In 1 condition
SPARTspartin	Always	In 1 condition
RSPRY1ring finger and SPRY domain containing 1	Often (30–79%)	In 1 condition
SONSON DNA and RNA binding protein	Sometimes (5–29%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Double jointed thumb1 gene

Broader traits

Small joint hypermobility

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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