Trait

Enlargement of half of face

Clinical name: Hemifacial hypertrophy

Unilateral overgrowth of facial tissues, including muscles, bones and skin.

HPO HP:0005323

Also called: Hemifacial enlargement, Hypertrophy of half of face, Increase in size of half of face, Overgrowth of half of face, Facial hemihypertophy
Body system: Abnormality of head or neck

This page as data

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library(jsonlite)

url <- "https://dantelabs.com/traits/hemifacial-hypertrophy.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

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1 gene linked to Enlargement of half of face

Changes in these genes cause rare conditions in which Enlargement of half of face is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
PIK3CAphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	Always	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Facial asymmetry

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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