{
  "url": "https://dantelabs.com/traits/hemifacial-hypertrophy",
  "trait": {
    "bundleId": "2026.10.17-8666dff2",
    "release": "2026-09-01",
    "slug": "hemifacial-hypertrophy",
    "id": "HP:0005323",
    "name": "Enlargement of half of face",
    "label": "Hemifacial hypertrophy",
    "definition": "Unilateral overgrowth of facial tissues, including muscles, bones and skin.",
    "synonyms": [
      "Hemifacial enlargement",
      "Hypertrophy of half of face",
      "Increase in size of half of face",
      "Overgrowth of half of face",
      "Facial hemihypertophy"
    ],
    "systems": [
      {
        "slug": "abnormality-of-head-or-neck",
        "name": "Abnormality of head or neck",
        "url": "https://dantelabs.com/traits/abnormality-of-head-or-neck"
      }
    ],
    "broader": [
      {
        "slug": "facial-asymmetry",
        "name": "Facial asymmetry",
        "url": "https://dantelabs.com/traits/facial-asymmetry"
      }
    ],
    "narrower": [],
    "genes": [
      {
        "slug": "pik3ca",
        "symbol": "PIK3CA",
        "hgnc": "HGNC:8975",
        "name": "phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha",
        "frequency": "obligate",
        "diseases": 1,
        "url": "https://dantelabs.com/genes/pik3ca"
      }
    ]
  }
}