Trait

Elevated urinary indican level

Detection of indican in the urine. Urinary indican concentration may be elevated in small bowel bacterial overgrowth. Indican is produced by bacterial deconjugation of dietary tryptophan to indole which is absorbed at all levels of the intestine, but principally from the small bowel.

HPO HP:6000130

Body system: Laboratory abnormality Abnormality of the genitourinary system

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2 genes linked to Elevated urinary indican level

Changes in these genes cause rare conditions in which Elevated urinary indican level is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
CLTRNcollectrin, amino acid transport regulator	Often (30–79%)	In 1 condition
SLC6A19solute carrier family 6 member 19	Often (30–79%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal urine metabolite level

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.17-8666dff2.

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