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Trait

Downgaze palsy

A limitation of the ability to direct one's gaze below the horizontal meridian.

HPO HP:0025330

Summary

Also called
Downgaze paresis, Supranuclear downgaze palsy
Body system
Abnormality of the eye

2 condition reports read genes linked to this trait

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1 gene linked to Downgaze palsy

Changes in these genes cause rare conditions in which Downgaze palsy is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

GeneHow often it is seenConditions
PIGTphosphatidylinositol glycan anchor biosynthesis class TSometimes (5–29%)In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Vertical supranuclear gaze palsy

Where this comes from

  • The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
  • Data release 2026.10.19-9814e911.

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