Trait
Decreased circulating IgG2 concentration
A reduction in immunoglobulin levels of the IgG2 subclass in the blood circulation.
Summary
- Also called
- Decreased circulating IgG2 level, Decreased IgG2 level in blood, Immunoglobulin IgG2 deficiency, Reduced IgG2 levels
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read the genes linked to Decreased circulating IgG2 concentration, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome Test12 genes linked to Decreased circulating IgG2 concentration
Changes in these genes cause rare conditions in which Decreased circulating IgG2 concentration is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| CD247CD247 molecule | Always | In 1 condition |
| CTPS1CTP synthase 1 | Always | In 1 condition |
| IKBKGinhibitor of nuclear factor kappa B kinase regulatory subunit gamma | Always | In 1 condition |
| SH3KBP1SH3 domain containing kinase binding protein 1 | Always | In 1 condition |
| PIK3CDphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta | Very often (80–99%) | In 1 condition |
| IKZF2IKAROS family zinc finger 2 | Often (30–79%) | In 1 condition |
| PIK3R1phosphoinositide-3-kinase regulatory subunit 1 | Often (30–79%) | In 1 condition |
| EPG5ectopic P-granules 5 autophagy tethering factor | Sometimes (5–29%) | In 2 conditions |
| KDM6Alysine demethylase 6A | Sometimes (5–29%) | In 1 condition |
| KMT2Dlysine methyltransferase 2D | Sometimes (5–29%) | In 1 condition |
| ADAadenosine deaminase | Not recorded | In 1 condition |
| ATMATM serine/threonine kinase | Not recorded | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Narrower traits
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks