Trait
Ankle weakness
Reduced strength of the muscles that lift or otherwise move the foot at the ankle.
Summary
- Body system
- Abnormality of the musculoskeletal system
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
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Get my Genome Test6 genes linked to Ankle weakness
Changes in these genes cause rare conditions in which Ankle weakness is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.
| Gene | How often it is seen | Conditions |
|---|---|---|
| MPV17mitochondrial inner membrane protein MPV17 | Always | In 1 condition |
| PMP22peripheral myelin protein 22 | Always | In 1 condition |
| MATR3matrin 3 | Often (30–79%) | In 1 condition |
| TTNtitin | Often (30–79%) | In 1 condition |
| BSCL2BSCL2 lipid droplet biogenesis associated, seipin | Sometimes (5–29%) | In 1 condition |
| LDB3LIM domain binding 3 | Sometimes (5–29%) | In 1 condition |
How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.
Broader traits
Where this comes from
- The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
- Data release 2026.10.16-c6eea6bf.
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