Trait

Absent corneal reflex

Absence of the corneal blinking reflex, which normally induces involuntary blinking of the eyelids following contact of the cornea. The corneal blink reflex is caused by a loop between the trigeminal sensory nerves and the facial motor (VII) nerve innervation of the orbicularis oculi muscles.

HPO HP:0034252

Body system: Abnormality of the eye

This page as data

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library(jsonlite)

url <- "https://dantelabs.com/traits/absent-corneal-reflex.json"
page <- fromJSON(url)
page$trait$name

Open the JSON

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3 genes linked to Absent corneal reflex

Changes in these genes cause rare conditions in which Absent corneal reflex is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
LIFRLIF receptor subunit alpha	Always	In 1 condition
NEUROG1neurogenin 1	Always	In 1 condition
DSTdystonin	Often (30–79%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Broader traits

Abnormal corneal reflex

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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