Trait

Abnormal granulocyte morphology

Any structural abnormality or abnormal count of granulocytes.

HPO HP:0001911

Also called: Abnormality of granulocytes
Body system: Abnormality of blood and blood-forming tissues Abnormality of the immune system

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5 genes linked to Abnormal granulocyte morphology

Changes in these genes cause rare conditions in which Abnormal granulocyte morphology is seen. Most people with this trait have none of those conditions, and a gene on this list says nothing about anyone's own genome.

Gene	How often it is seen	Conditions
NLRP3NLR family pyrin domain containing 3	Very often (80–99%)	In 1 condition
ABHD5abhydrolase domain containing 5, lysophosphatidic acid acyltransferase	Often (30–79%)	In 1 condition
ABL1ABL proto-oncogene 1, non-receptor tyrosine kinase	Often (30–79%)	In 1 condition
BCRBCR activator of RhoGEF and GTPase	Often (30–79%)	In 1 condition
RUNX1RUNX family transcription factor 1	Often (30–79%)	In 1 condition

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Narrower traits

Broader traits

Abnormal myeloid leukocyte morphology

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the trait, its names, its definition and the genes linked to it. Find out more at hpo.jax.org.
Data release 2026.10.16-c6eea6bf.

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