Gene
ZIC4
Zic family zinc finger 4
- HGNC 20393↗(opens in a new tab)
- Ensembl gene ENSG00000174963↗(opens in a new tab)
- NCBI Gene 84107↗(opens in a new tab)
Summary
- Cytogenetic location
- 3q24
- Coordinates
- Chromosome 3: 147,386,046–147,406,543 (GRCh38)
- Exons
- 5 exons across 20.5 kb
- Protein
- 334 amino acids
- MANE Select transcript
- ENST00000383075.8NM_032153.6
- Locus type
- gene with protein product
- Very high
- Confident
- Low
- Very low
Reference genomeGRCh38hg38
Positions on gene and variant pages follow this choice, in this browser.
Read ZIC4, and the rest of your genome, with one test.
From $449Free shipping · Results in 6–8 weeks
Get my Genome TestCurated reports relevant to this gene
No Genome Test report reads ZIC4 yet. The test sequences your whole genome, so your data includes it all the same.
How ZIC4 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 4 kb of the gene's 20.5 kb; 1,005 of those bases code for the protein.
Traits linked to ZIC4
The Human Phenotype Ontology lists these as features of the rare conditions ZIC4 can cause. Each trait's page lists the other genes linked to it.
Abnormality of the nervous system
- Too much cerebrospinal fluid in the brain
- Aplasia/Hypoplasia of the cerebellar vermis
- Dilated fourth ventricle
- Small cerebellum
- Aplasia/Hypoplasia of the corpus callosum
- Intellectual disability
- Motor delay
- Rise in pressure inside skull
Show 1 more trait
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.
Cite this page
Dante Labs. (n.d.). ZIC4 gene: Zic family zinc finger 4. Retrieved 17 October 2026, from https://dantelabs.com/genes/zic4
Dante Labs. ZIC4 gene: Zic family zinc finger 4 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/zic4
One test. A lifetime of answers.
From $449Free shipping · Results in 6–8 weeks