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Gene

VPS4B

vacuolar protein sorting 4 homolog B

Summary

Cytogenetic location
18q21.33
Coordinates
Chromosome 18: 63,389,190–63,422,476 (GRCh38)
Exons
11 exons across 33.3 kb
Protein
444 amino acids
Also known as
VPS4-2, SKD1B
Previous symbols
SKD1
MANE Select transcript
ENST00000238497.10NM_004869.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads VPS4B yet. The test sequences your whole genome, so your data includes it all the same.

How VPS4B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 18, with a bracket where VPS4B sits. VPS4B and 12 genes near it on chromosome 18, from 62,905,833 to 63,905,832.Chromosome 1818q21.33p11.32p11.31p11.23p11.22p11.21p11.1q11.1q11.2q12.1q12.2q12.3q21.1q21.2q21.31q21.32q21.33q22.1q22.2q22.3q2363 Mb63.2 Mb63.4 Mb63.6 Mb63.8 MbPHLPP1: 62,715,424–62,980,433, forward strandPHLPP1BCL2: 63,123,346–63,320,215, reverse strandBCL2KDSR: 63,327,566–63,367,615, reverse strandKDSRVPS4B: 63,389,190–63,422,476, reverse strandVPS4BSERPINB5: 63,476,817–63,505,085, forward strandSERPINB5SERPINB12: 63,542,369–63,569,329, forward strandSERPINB12SERPINB13: 63,586,654–63,604,639, forward strandSERPINB13SERPINB4: 63,637,259–63,644,263, reverse strandSERPINB4SERPINB11: 63,647,579–63,726,432, forward strandSERPINB11SERPINB3: 63,652,584–63,661,893, reverse strandSERPINB3SERPINB7: 63,752,935–63,805,376, forward strandSERPINB7SERPINB2: 63,871,692–63,903,888, forward strandSERPINB2: 63,897,174–63,917,490, forward strandDiagram of VPS4B: 11 exons on the reverse strand of chromosome 18Exon 11: 63,389,190–63,391,076, 1,887 basesExon 10: 63,393,409–63,393,549, 141 basesExon 9: 63,397,034–63,397,253, 220 basesExon 8: 63,399,242–63,399,323, 82 basesExon 7: 63,400,048–63,400,196, 149 basesExon 6: 63,400,547–63,400,703, 157 basesExon 5: 63,403,707–63,403,826, 120 basesExon 4: 63,407,432–63,407,499, 68 basesExon 3: 63,410,290–63,410,446, 157 basesExon 2: 63,411,467–63,411,578, 112 basesExon 1: 63,422,233–63,422,476, 244 bases1110864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.3 kb of the gene's 33.3 kb; 1,335 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). VPS4B gene: vacuolar protein sorting 4 homolog B. Retrieved 17 October 2026, from https://dantelabs.com/genes/vps4b

Vancouver

Dante Labs. VPS4B gene: vacuolar protein sorting 4 homolog B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/vps4b

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