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Gene

TTLL1

TTL family tubulin polyglutamylase complex subunit L1

Summary

Cytogenetic location
22q13.2
Coordinates
Chromosome 22: 43,039,516–43,089,391 (GRCh38)
Exons
11 exons across 49.9 kb
Protein
423 amino acids
Also known as
PGs3, TPGS3
Previous symbols
C22orf7
MANE Select transcript
ENST00000266254.12NM_012263.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TTLL1 yet. The test sequences your whole genome, so your data includes it all the same.

How TTLL1 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 22, with a bracket where TTLL1 sits. TTLL1 and 16 genes near it on chromosome 22, from 42,564,454 to 43,564,453.Chromosome 2222q13.2p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3342.6 Mb42.8 Mb43 Mb43.2 Mb43.4 MbSERHL2: 42,553,617–42,574,387, forward strandSERHL2POLDIP3: 42,582,750–42,614,962, reverse strand: 42,583,836–42,627,688, reverse strandRNU12: 42,615,244–42,615,393, forward strandRNU12CYB5R3: 42,615,730–42,720,870, reverse strandCYB5R3ATP5MGL: 42,639,803–42,640,601, reverse strandATP5MGLA4GALT: 42,691,010–42,721,298, reverse strandA4GALTARFGAP3: 42,796,502–42,858,106, reverse strandARFGAP3PACSIN2: 42,835,412–43,015,185, reverse strandPACSIN2TTLL1: 43,039,516–43,089,391, reverse strandTTLL1BIK: 43,110,742–43,129,712, forward strandBIKMCAT: 43,130,627–43,143,401, reverse strandMCATTSPO: 43,151,077–43,163,246, forward strandTSPOTTLL12: 43,164,366–43,187,160, reverse strandTTLL12SCUBE1: 43,197,280–43,343,379, reverse strandSCUBE1MPPED1: 43,411,196–43,507,850, forward strandMPPED1EFCAB6: 43,528,744–43,812,337, reverse strandEFCAB6Diagram of TTLL1: 11 exons on the reverse strand of chromosome 22Exon 11: 43,039,516–43,039,905, 390 basesExon 10: 43,046,410–43,046,573, 164 basesExon 9: 43,051,801–43,051,887, 87 basesExon 8: 43,059,384–43,059,527, 144 basesExon 7: 43,063,813–43,063,921, 109 basesExon 6: 43,064,190–43,064,324, 135 basesExon 5: 43,068,410–43,068,590, 181 basesExon 4: 43,069,636–43,069,844, 209 basesExon 3: 43,075,474–43,075,590, 117 basesExon 2: 43,079,902–43,079,986, 85 basesExon 1: 43,089,277–43,089,391, 115 bases1110864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.7 kb of the gene's 49.9 kb; 1,272 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TTLL1 gene: TTL family tubulin polyglutamylase complex subunit L1. Retrieved 17 October 2026, from https://dantelabs.com/genes/ttll1

Vancouver

Dante Labs. TTLL1 gene: TTL family tubulin polyglutamylase complex subunit L1 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ttll1

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