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Gene

TTC3

tetratricopeptide repeat domain 3

Summary

Cytogenetic location
21q22.13
Coordinates
Chromosome 21: 37,073,254–37,203,107 (GRCh38)
Exons
46 exons across 129.9 kb
Protein
2,025 amino acids
Also known as
TPRD, TPRDI, DCRR1, TPRDII, TPRDIII, RNF105
MANE Select transcript
ENST00000418766.6NM_001330683.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TTC3 yet. The test sequences your whole genome, so your data includes it all the same.

How TTC3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 21, with a bracket where TTC3 sits. TTC3 and 7 genes near it on chromosome 21, from 36,638,181 to 37,638,180.Chromosome 2121q22.13p13p12p11.2p11.1q11.1q11.2q21.1q21.2q21.3q22.11q22.12q22.13q22.2q22.336.8 Mb37 Mb37.2 Mb37.4 Mb37.6 MbSIM2: 36,699,104–36,751,135, forward strandSIM2HLCS: 36,748,626–36,990,236, reverse strandHLCSRIPPLY3: 37,006,150–37,019,662, forward strandRIPPLY3PIGP: 37,036,533–37,073,820, reverse strandPIGPTTC3: 37,073,254–37,203,107, forward strandTTC3VPS26C: 37,221,749–37,268,104, reverse strandVPS26CDYRK1A: 37,365,573–37,526,358, forward strandDYRK1AKCNJ6: 37,607,373–38,121,345, reverse strandKCNJ6Diagram of TTC3: 46 exons on the forward strand of chromosome 21Exon 1: 37,073,254–37,073,473, 220 basesExon 2: 37,087,247–37,087,401, 155 basesExon 3: 37,087,833–37,087,875, 43 basesExon 4: 37,088,196–37,088,346, 151 basesExon 5: 37,088,799–37,088,886, 88 basesExon 6: 37,090,233–37,090,286, 54 basesExon 7: 37,091,293–37,091,413, 121 basesExon 8: 37,094,005–37,094,090, 86 basesExon 9: 37,095,350–37,095,444, 95 basesExon 10: 37,096,581–37,096,643, 63 basesExon 11: 37,108,392–37,108,446, 55 basesExon 12: 37,121,817–37,121,979, 163 basesExon 13: 37,122,983–37,123,028, 46 basesExon 14: 37,124,619–37,124,742, 124 basesExon 15: 37,126,080–37,126,143, 64 basesExon 16: 37,129,003–37,129,063, 61 basesExon 17: 37,132,682–37,132,766, 85 basesExon 18: 37,135,380–37,135,514, 135 basesExon 19: 37,138,634–37,138,714, 81 basesExon 20: 37,140,561–37,140,673, 113 basesExon 21: 37,144,525–37,144,645, 121 basesExon 22: 37,147,481–37,147,603, 123 basesExon 23: 37,148,546–37,148,647, 102 basesExon 24: 37,150,078–37,150,170, 93 basesExon 25: 37,150,820–37,150,884, 65 basesExon 26: 37,151,893–37,152,029, 137 basesExon 27: 37,152,951–37,153,277, 327 basesExon 28: 37,156,655–37,156,906, 252 basesExon 29: 37,159,699–37,159,745, 47 basesExon 30: 37,160,802–37,160,858, 57 basesExon 31: 37,161,990–37,162,063, 74 basesExon 32: 37,164,051–37,164,215, 165 basesExon 33: 37,165,550–37,166,615, 1,066 basesExon 34: 37,167,555–37,167,620, 66 basesExon 35: 37,172,595–37,172,744, 150 basesExon 36: 37,182,774–37,182,913, 140 basesExon 37: 37,185,706–37,185,774, 69 basesExon 38: 37,187,049–37,187,145, 97 basesExon 39: 37,188,495–37,188,595, 101 basesExon 40: 37,191,334–37,191,424, 91 basesExon 41: 37,192,112–37,192,213, 102 basesExon 42: 37,195,675–37,196,036, 362 basesExon 43: 37,197,570–37,197,696, 127 basesExon 44: 37,197,882–37,198,025, 144 basesExon 45: 37,200,232–37,200,324, 93 basesExon 46: 37,201,440–37,203,107, 1,668 bases110203040465′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 7.8 kb of the gene's 129.9 kb; 6,078 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TTC3 gene: tetratricopeptide repeat domain 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/ttc3

Vancouver

Dante Labs. TTC3 gene: tetratricopeptide repeat domain 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ttc3

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