Gene
TNRC18
trinucleotide repeat containing 18
- HGNC 11962↗(opens in a new tab)
- Ensembl gene ENSG00000182095↗(opens in a new tab)
- NCBI Gene 84629↗(opens in a new tab)
Summary
- Cytogenetic location
- 7p22.1
- Coordinates
- Chromosome 7: 5,306,811–5,423,834 (GRCh38)
- Exons
- 30 exons across 117 kb
- Protein
- 2,968 amino acids
- Also known as
- CAGL79, TNRC18A, KIAA1856
- MANE Select transcript
- ENST00000430969.6NM_001080495.3
- Locus type
- Protein-coding
This page as data
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How TNRC18 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
- Stretches short reads find hard
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 10.8 kb of the gene's 117 kb; 8,907 of those bases code for the protein.
Sequencing TNRC18
45Hard
How hard TNRC18 is to sequence with short reads, out of 100
0 · Easy100 · Hard
Much of TNRC18 sits where short reads can miss or misplace a change.
What adds to it: the share of TNRC18's exons in each kind of hard region
- MappabilityStretches where 100 or 250 bp reads cannot be placed uniquely, so a call there may be missing or wrong. Weight 100%.10%
- HomologySegmental duplications: copies elsewhere in the genome, such as paralogues and pseudogenes, at 90% identity or more. Weight 60%.43%
- Shared with chrYThe pseudoautosomal regions and the X-transposed region, where chrX and chrY carry the same or nearly the same sequence, so reads from either may land on the other. Weight 60%.0%
- Reference coverageGaps in the reference assembly nearby, where there is no sequence for reads to align to. Weight 50%.0%
- RepeatsTandem repeats and runs of one base, which reads slip on and may not span. Weight 30%.6.9%
- GC contentWindows under 25% or over 65% G and C, which library preparation covers thinly. Weight 20%.77%
A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scoredEach bar is the share of TNRC18's exon bases in that kind of difficult region. Any one kind can make a gene hard on its own, and each further kind adds less: 0 when no base is in any, 100 when every base is where reads cannot be placed uniquely.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
Cite this page
Dante Labs. (n.d.). TNRC18 gene: trinucleotide repeat containing 18. Retrieved 19 October 2026, from https://dantelabs.com/genes/tnrc18
Dante Labs. TNRC18 gene: trinucleotide repeat containing 18 [Internet]. [cited 19 October 2026]. Available from: https://dantelabs.com/genes/tnrc18
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