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Gene

TMEM121B

transmembrane protein 121B

Summary

Cytogenetic location
22q11.1
Coordinates
Chromosome 22: 17,116,297–17,121,360 (GRCh38)
Exons
1 exon across 5.1 kb
Protein
578 amino acids
Previous symbols
CECR6
MANE Select transcript
ENST00000331437.4NM_031890.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads TMEM121B yet. The test sequences your whole genome, so your data includes it all the same.

How TMEM121B is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 22, with a bracket where TMEM121B sits. TMEM121B and 8 genes near it on chromosome 22, from 16,618,829 to 17,618,828.Chromosome 2222q11.1p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3316.8 Mb17 Mb17.2 Mb17.4 Mb17.6 MbXKR3: 16,783,412–16,851,222, reverse strandXKR3GAB4: 16,961,936–17,008,222, reverse strandGAB4IL17RA: 17,084,934–17,115,693, forward strandIL17RATMEM121B: 17,116,297–17,121,360, reverse strandTMEM121BHDHD5: 17,132,107–17,165,287, reverse strandHDHD5ADA2: 17,178,790–17,258,235, reverse strandADA2CECR2: 17,359,949–17,558,151, forward strandCECR2SLC25A18: 17,562,670–17,591,927, forward strandSLC25A18ATP6V1E1: 17,592,136–17,630,958, reverse strandATP6V1E1Diagram of TMEM121B: one exon on the reverse strand of chromosome 22Exon 1: 17,116,297–17,121,360, 5,064 bases15′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.1 kb of the gene's 5.1 kb; 1,737 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TMEM121B gene: transmembrane protein 121B. Retrieved 17 October 2026, from https://dantelabs.com/genes/tmem121b

Vancouver

Dante Labs. TMEM121B gene: transmembrane protein 121B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tmem121b

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