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Gene

TMEM121

transmembrane protein 121

Summary

Cytogenetic location
14q32.33
Coordinates
Chromosome 14: 105,526,583–105,530,198 (GRCh38)
Exons
2 exons across 3.6 kb
Protein
319 amino acids
Also known as
MGC4659, hole, hhole, TMEM121A
MANE Select transcript
ENST00000392519.7NM_025268.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TMEM121 yet. The test sequences your whole genome, so your data includes it all the same.

How TMEM121 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 14, with a bracket where TMEM121 sits. TMEM121 and 14 genes near it on chromosome 14, from 105,028,391 to 106,028,390.Chromosome 1414q32.33p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q21.1q21.2q21.3q22.1q22.2q22.3q23.1q23.2q23.3q24.1q24.2q24.3q31.1q31.2q31.3q32.11q32.12q32.13q32.2q32.31q32.32q32.33105.2 Mb105.4 Mb105.6 Mb105.8 Mb106 MbCDCA4: 105,008,532–105,033,828, reverse strandCDCA4GPR132: 105,048,658–105,065,940, reverse strandGPR132JAG2: 105,140,982–105,168,919, reverse strandJAG2NUDT14: 105,172,937–105,181,323, reverse strandNUDT14BRF1: 105,209,277–105,315,589, reverse strandBRF1BTBD6: 105,248,533–105,251,125, forward strandBTBD6PACS2: 105,300,563–105,398,147, forward strandPACS2TEX22: 105,398,525–105,450,106, forward strandTEX22MTA1: 105,419,808–105,470,737, forward strandMTA1CRIP2: 105,472,940–105,480,170, forward strandCRIP1: 105,480,346–105,488,947, forward strandCRIP1: 105,487,199–105,492,267, forward strandTEDC1: 105,489,855–105,501,129, forward strandTEDC1TMEM121: 105,526,583–105,530,198, forward strandTMEM121IGHM: 105,851,705–105,856,218, reverse strandIGHMDiagram of TMEM121: 2 exons on the forward strand of chromosome 14Exon 1: 105,526,583–105,526,653, 71 basesExon 2: 105,528,722–105,530,198, 1,477 bases125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 1.5 kb of the gene's 3.6 kb; 960 of those bases code for the protein.

Sequencing TMEM121

12Moderate

How hard TMEM121 is to sequence with short reads, out of 100

  • Mappability0%
  • Homology0%
  • Repeats17%
  • GC content100%
  • Reference coverage0%

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). TMEM121 gene: transmembrane protein 121. Retrieved 17 October 2026, from https://dantelabs.com/genes/tmem121

Vancouver

Dante Labs. TMEM121 gene: transmembrane protein 121 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tmem121

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