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Gene

TIGIT

T cell immunoreceptor with Ig and ITIM domains

Summary

Cytogenetic location
3q13.31
Coordinates
Chromosome 3: 114,294,028–114,310,288 (GRCh38)
Exons
4 exons across 16.3 kb
Protein
244 amino acids
Also known as
FLJ39873, DKFZp667A205
Previous symbols
VSIG9, VSTM3
MANE Select transcript
ENST00000383671.8NM_173799.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads TIGIT yet. The test sequences your whole genome, so your data includes it all the same.

How TIGIT is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 3, with a bracket where TIGIT sits. TIGIT and 8 genes near it on chromosome 3, from 113,802,158 to 114,802,157.Chromosome 33q13.31p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q29114 Mb114.2 Mb114.4 Mb114.6 Mb114.8 MbATP6V1A: 113,746,296–113,812,251, forward strandATP6V1AGRAMD1C: 113,828,182–113,947,179, forward strandGRAMD1CZDHHC23: 113,947,706–113,965,401, forward strandZDHHC23CCDC191: 113,964,137–114,056,594, reverse strandCCDC191QTRT2: 114,005,833–114,088,542, forward strandQTRT2DRD3: 114,127,580–114,199,407, reverse strandDRD3ZNF80: 114,234,631–114,237,578, reverse strandZNF80TIGIT: 114,294,028–114,310,288, forward strandTIGITZBTB20: 114,314,500–115,147,356, reverse strandZBTB20Diagram of TIGIT: 4 exons on the forward strand of chromosome 3Exon 1: 114,294,028–114,294,122, 95 basesExon 2: 114,295,545–114,295,874, 330 basesExon 3: 114,299,597–114,299,703, 107 basesExon 4: 114,307,895–114,310,288, 2,394 bases12345′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 2.9 kb of the gene's 16.3 kb; 735 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). TIGIT gene: T cell immunoreceptor with Ig and ITIM domains. Retrieved 17 October 2026, from https://dantelabs.com/genes/tigit

Vancouver

Dante Labs. TIGIT gene: T cell immunoreceptor with Ig and ITIM domains [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/tigit

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