Traits

Traits linked to TF

transferrin

The Human Phenotype Ontology links 10 traits to TF, by body system: features seen in people with one of the gene's rare conditions.

Abnormality of blood and blood-forming tissues

Trait	How often it is seen
Low number of red blood cells or hemoglobin	Very often (80–99%)
Hypochromic anemia	Not recorded

Abnormality of the cardiovascular system

Trait	How often it is seen
Abnormality of the cardiovascular system	Sometimes (5–29%)
Cardiac failure	Not recorded

Abnormality of the digestive system

Trait	How often it is seen
Abnormality of the pancreas	Sometimes (5–29%)
Abnormality of the liver	Not recorded

Abnormality of the endocrine system

Trait	How often it is seen
Underactive thyroid	Sometimes (5–29%)

Abnormality of the immune system

Trait	How often it is seen
Recurrent infections	Often (30–79%)

Abnormality of the musculoskeletal system

Trait	How often it is seen
Arthritis	Sometimes (5–29%)

Laboratory abnormality

Trait	How often it is seen
Atransferrinemia	Not recorded

How often is among people with one of the gene's conditions, the most often across them, as the Human Phenotype Ontology records it. These pages describe traits and the research behind them; they are not a diagnosis, and a doctor or genetic counsellor is the person to ask about symptoms.

Where this comes from

The Human Phenotype Ontology, release 2026-09-01: the traits linked to TF and how often each is seen. Find out more at hpo.jax.org.

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