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Gene

SPTLC3

serine palmitoyltransferase long chain base subunit 3

Summary

Cytogenetic location
20p12.1
Coordinates
Chromosome 20: 13,008,972–13,169,103 (GRCh38)
Exons
12 exons across 160.1 kb
Protein
552 amino acids
Also known as
LCB2B, FLJ11112, hLCB2b
Previous symbols
C20orf38, SPTLC2L
MANE Select transcript
ENST00000399002.7NM_018327.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SPTLC3 yet. The test sequences your whole genome, so your data includes it all the same.

How SPTLC3 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 20, with a bracket where SPTLC3 sits. SPTLC3 and 2 genes near it on chromosome 20, from 12,589,038 to 13,589,037.Chromosome 2020p12.1p13p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12q13.11q13.12q13.13q13.2q13.31q13.32q13.3312.6 Mb12.8 Mb13 Mb13.2 Mb13.4 MbSPTLC3: 13,008,972–13,169,103, forward strandSPTLC3ISM1: 13,221,258–13,300,651, forward strandISM1TASP1: 13,387,216–13,639,109, reverse strandTASP1Diagram of SPTLC3: 12 exons on the forward strand of chromosome 20Exon 1: 13,008,972–13,009,384, 413 basesExon 2: 13,048,945–13,049,130, 186 basesExon 3: 13,072,256–13,072,410, 155 basesExon 4: 13,074,349–13,074,497, 149 basesExon 5: 13,091,083–13,091,207, 125 basesExon 6: 13,093,484–13,093,577, 94 basesExon 7: 13,110,112–13,110,217, 106 basesExon 8: 13,117,506–13,117,725, 220 basesExon 9: 13,126,591–13,126,717, 127 basesExon 10: 13,154,003–13,154,138, 136 basesExon 11: 13,160,003–13,160,132, 130 basesExon 12: 13,164,754–13,169,103, 4,350 bases1246810125′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 6.2 kb of the gene's 160.1 kb; 1,659 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SPTLC3 gene: serine palmitoyltransferase long chain base subunit 3. Retrieved 17 October 2026, from https://dantelabs.com/genes/sptlc3

Vancouver

Dante Labs. SPTLC3 gene: serine palmitoyltransferase long chain base subunit 3 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sptlc3

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