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Gene

SMC4

structural maintenance of chromosomes 4

Summary

Cytogenetic location
3q25.33
Coordinates
Chromosome 3: 160,399,650–160,434,953 (GRCh38)
Exons
24 exons across 35.3 kb
Protein
1,288 amino acids
Also known as
hCAP-C, CAP-C
Previous symbols
SMC4L1
MANE Select transcript
ENST00000357388.8NM_001002800.3
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads SMC4 yet. The test sequences your whole genome, so your data includes it all the same.

How SMC4 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 3, with a bracket where SMC4 sits. SMC4 and 8 genes near it on chromosome 3, from 159,917,302 to 160,917,301.Chromosome 33q25.33p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q29160 Mb160.2 Mb160.4 Mb160.6 Mb160.8 MbIL12A: 159,988,830–159,996,019, forward strandIL12AC3orf80: 160,225,422–160,228,213, forward strandC3orf80TRIM59-IFT80: 160,227,454–160,449,829, reverse strandTRIM59-IFT80IFT80: 160,256,986–160,400,357, reverse strandIFT80SMC4: 160,399,650–160,434,953, forward strandSMC4TRIM59: 160,432,445–160,485,773, reverse strandTRIM59KPNA4: 160,495,007–160,565,591, reverse strandKPNA4ARL14: 160,677,160–160,678,448, forward strandARL14PPM1L: 160,755,526–161,078,902, forward strandPPM1LDiagram of SMC4: 24 exons on the forward strand of chromosome 3Exon 1: 160,399,650–160,399,749, 100 basesExon 2: 160,400,822–160,400,965, 144 basesExon 3: 160,401,915–160,402,093, 179 basesExon 4: 160,402,676–160,402,867, 192 basesExon 5: 160,404,328–160,404,504, 177 basesExon 6: 160,411,920–160,412,084, 165 basesExon 7: 160,412,326–160,412,453, 128 basesExon 8: 160,413,473–160,413,613, 141 basesExon 9: 160,414,367–160,414,517, 151 basesExon 10: 160,416,251–160,416,415, 165 basesExon 11: 160,417,723–160,417,956, 234 basesExon 12: 160,419,358–160,419,543, 186 basesExon 13: 160,420,740–160,420,901, 162 basesExon 14: 160,423,425–160,423,650, 226 basesExon 15: 160,423,761–160,423,840, 80 basesExon 16: 160,424,867–160,425,019, 153 basesExon 17: 160,426,074–160,426,200, 127 basesExon 18: 160,428,753–160,428,942, 190 basesExon 19: 160,430,599–160,430,743, 145 basesExon 20: 160,431,032–160,431,205, 174 basesExon 21: 160,431,643–160,431,825, 183 basesExon 22: 160,432,283–160,432,515, 233 basesExon 23: 160,433,026–160,433,209, 184 basesExon 24: 160,433,657–160,434,953, 1,297 bases1246810121416182022245′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 5.1 kb of the gene's 35.3 kb; 3,867 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SMC4 gene: structural maintenance of chromosomes 4. Retrieved 17 October 2026, from https://dantelabs.com/genes/smc4

Vancouver

Dante Labs. SMC4 gene: structural maintenance of chromosomes 4 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/smc4

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