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Gene

PPM1L

protein phosphatase, Mg2+/Mn2+ dependent 1L

Summary

Cytogenetic location
3q25.33-q26.1
Coordinates
Chromosome 3: 160,756,231–161,078,902 (GRCh38)
Exons
4 exons across 322.7 kb
Protein
360 amino acids
Also known as
PP2CE
MANE Select transcript
ENST00000498165.6NM_139245.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PPM1L yet. The test sequences your whole genome, so your data includes it all the same.

How PPM1L is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 3, with a bracket where PPM1L sits. PPM1L and 8 genes near it on chromosome 3, from 160,417,567 to 161,417,566.Chromosome 33q25.33-q26.1p26.3p26.2p26.1p25.3p25.2p25.1p24.3p24.2p24.1p23p22.3p22.2p22.1p21.33p21.32p21.31p21.2p21.1p14.3p14.2p14.1p13p12.3p12.2p12.1p11.2p11.1q11.1q11.2q12.1q12.2q12.3q13.11q13.12q13.13q13.2q13.31q13.32q13.33q21.1q21.2q21.3q22.1q22.2q22.3q23q24q25.1q25.2q25.31q25.32q25.33q26.1q26.2q26.31q26.32q26.33q27.1q27.2q27.3q28q29160.6 Mb160.8 Mb161 Mb161.2 Mb161.4 MbTRIM59-IFT80: 160,227,454–160,449,829, reverse strandTRIM59-IFT80SMC4: 160,399,274–160,437,759, forward strandSMC4TRIM59: 160,432,445–160,485,773, reverse strandTRIM59KPNA4: 160,495,007–160,565,591, reverse strandKPNA4ARL14: 160,677,160–160,678,448, forward strandARL14PPM1L: 160,756,231–161,078,902, forward strandPPM1LB3GALNT1: 161,083,565–161,105,445, reverse strandB3GALNT1NMD3: 161,104,675–161,284,991, forward strandNMD3SPTSSB: 161,344,798–161,372,941, reverse strandSPTSSBDiagram of PPM1L: 4 exons on the forward strand of chromosome 3Exon 1: 160,756,231–160,756,707, 477 basesExon 2: 160,961,736–160,961,910, 175 basesExon 3: 161,065,403–161,065,564, 162 basesExon 4: 161,068,811–161,078,902, 10,092 bases12345′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 10.9 kb of the gene's 322.7 kb; 1,083 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PPM1L gene: protein phosphatase, Mg2+/Mn2+ dependent 1L. Retrieved 17 October 2026, from https://dantelabs.com/genes/ppm1l

Vancouver

Dante Labs. PPM1L gene: protein phosphatase, Mg2+/Mn2+ dependent 1L [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ppm1l

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