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Gene

SIRPA

signal regulatory protein alpha

Summary

Cytogenetic location
20p13
Coordinates
Chromosome 20: 1,895,407–1,940,592 (GRCh38)
Exons
8 exons across 45.2 kb
Protein
504 amino acids
Also known as
SHPS1, SIRP, MYD-1, BIT, P84, SHPS-1, SIRPalpha, CD172a, SIRPalpha2, MFR, SIRP-ALPHA-1
Previous symbols
PTPNS1
MANE Select transcript
ENST00000358771.5NM_001040023.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads SIRPA yet. The test sequences your whole genome, so your data includes it all the same.

How SIRPA is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 20, with a bracket where SIRPA sits. SIRPA and 11 genes near it on chromosome 20, from 1,418,000 to 2,417,999.Chromosome 2020p13p13p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11.1q11.21q11.22q11.23q12q13.11q13.12q13.13q13.2q13.31q13.32q13.331.6 Mb1.8 Mb2 Mb2.2 Mb2.4 MbNSFL1C: 1,442,162–1,473,842, reverse strandNSFL1CSIRPB2: 1,470,741–1,491,587, reverse strandSIRPB2SIRPD: 1,534,251–1,557,705, reverse strandSIRPD: 1,540,144–1,620,009, reverse strandSIRPB1: 1,561,385–1,620,061, reverse strandSIRPB1SIRPG: 1,629,152–1,657,779, reverse strandSIRPGSIRPA: 1,895,407–1,940,592, forward strandSIRPAPDYN: 1,978,757–1,994,692, reverse strandPDYNSTK35: 2,101,767–2,177,038, forward strandSTK35: 2,207,328–2,341,059, forward strandTGM3: 2,295,994–2,341,177, forward strandTGM3TGM6: 2,380,901–2,432,753, forward strandTGM6Diagram of SIRPA: 8 exons on the forward strand of chromosome 20Exon 1: 1,895,407–1,895,526, 120 basesExon 2: 1,915,099–1,915,455, 357 basesExon 3: 1,921,395–1,921,712, 318 basesExon 4: 1,922,313–1,922,645, 333 basesExon 5: 1,924,764–1,924,877, 114 basesExon 6: 1,927,875–1,927,899, 25 basesExon 7: 1,934,715–1,934,754, 40 basesExon 8: 1,937,320–1,940,592, 3,273 bases123456785′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.6 kb of the gene's 45.2 kb; 1,515 of those bases code for the protein.

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). SIRPA gene: signal regulatory protein alpha. Retrieved 17 October 2026, from https://dantelabs.com/genes/sirpa

Vancouver

Dante Labs. SIRPA gene: signal regulatory protein alpha [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/sirpa

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