Gene
RNF103
ring finger protein 103
- HGNC 12859↗(opens in a new tab)
- Ensembl gene ENSG00000239305↗(opens in a new tab)
- NCBI Gene 7844↗(opens in a new tab)
Summary
- Cytogenetic location
- 2p11.2
- Coordinates
- Chromosome 2: 86,603,398–86,623,865 (GRCh38)
- Exons
- 4 exons across 20.5 kb
- Protein
- 685 amino acids
- Also known as
- hkf-1, KF1
- Previous symbols
- ZFP103
- MANE Select transcript
- ENST00000237455.5NM_005667.4
- Locus type
- Protein-coding
- Very high
- Confident
- Low
- Very low
This page as data
Add .json to the page's address, or ask for application/json, to read it as JSON.
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How RNF103 is laid out
- Coding sequence
- Untranslated region
- Intron
- Direction of transcription
Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.
Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).
Nearby genes from Ensembl release 116, on GRCh38.
Exons make up 3.5 kb of the gene's 20.5 kb; 2,058 of those bases code for the protein.
Sequencing RNF103
7Easy
How hard RNF103 is to sequence with short reads, out of 100
0 · Easy100 · Hard
Almost all of RNF103's exons sit where short reads map cleanly.
What adds to it: the share of RNF103's exons in each kind of hard region
- MappabilityStretches where 100 or 250 bp reads cannot be placed uniquely, so a call there may be missing or wrong. Weight 100%.0%
- HomologySegmental duplications: copies elsewhere in the genome, such as paralogues and pseudogenes, at 90% identity or more. Weight 60%.0%
- Shared with chrYThe pseudoautosomal regions and the X-transposed region, where chrX and chrY carry the same or nearly the same sequence, so reads from either may land on the other. Weight 60%.0%
- Reference coverageGaps in the reference assembly nearby, where there is no sequence for reads to align to. Weight 50%.0%
- RepeatsTandem repeats and runs of one base, which reads slip on and may not span. Weight 30%.5.6%
- GC contentWindows under 25% or over 65% G and C, which library preparation covers thinly. Weight 20%.28%
A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scoredEach bar is the share of RNF103's exon bases in that kind of difficult region. Any one kind can make a gene hard on its own, and each further kind adds less: 0 when no base is in any, 100 when every base is where reads cannot be placed uniquely.
External links
Gene records
Transcript
Protein
Where this comes from
- HGNC: the gene's symbol, name, other symbols and location.
- MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
- The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.
Cite this page
Dante Labs. (n.d.). RNF103 gene: ring finger protein 103. Retrieved 19 October 2026, from https://dantelabs.com/genes/rnf103
Dante Labs. RNF103 gene: ring finger protein 103 [Internet]. [cited 19 October 2026]. Available from: https://dantelabs.com/genes/rnf103
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