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Gene

RNASEL

ribonuclease L

Summary

Cytogenetic location
1q25.3
Coordinates
Chromosome 1: 182,573,634–182,589,256 (GRCh38)
Exons
7 exons across 15.6 kb
Protein
741 amino acids
Previous symbols
RNS4, PRCA1
MANE Select transcript
ENST00000367559.7NM_021133.4
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Trait report that reads RNASEL

How RNASEL is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 1, with a bracket where RNASEL sits. RNASEL and 9 genes near it on chromosome 1, from 182,081,445 to 183,081,444.Chromosome 11q25.3p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q44182.2 Mb182.4 Mb182.6 Mb182.8 Mb183 MbGLUL: 182,378,098–182,392,206, reverse strandGLULTEDDM1: 182,398,117–182,400,667, reverse strandTEDDM1RGSL1: 182,409,192–182,560,599, forward strandRGSL1RNASEL: 182,573,634–182,589,256, reverse strandRNASELRGS16: 182,598,623–182,604,394, reverse strandRGS16RGS8: 182,641,816–182,684,587, reverse strandRGS8NPL: 182,789,263–182,831,017, forward strandNPLDHX9: 182,839,302–182,888,120, forward strandDHX9SHCBP1L: 182,899,865–182,953,525, reverse strandSHCBP1LLAMC1: 183,023,199–183,145,592, forward strandLAMC1Diagram of RNASEL: 7 exons on the reverse strand of chromosome 1Exon 7: 182,573,634–182,575,578, 1,945 basesExon 6: 182,576,256–182,576,389, 134 basesExon 5: 182,581,225–182,581,357, 133 basesExon 4: 182,582,053–182,582,258, 206 basesExon 3: 182,584,081–182,584,166, 86 basesExon 2: 182,585,327–182,586,970, 1,644 basesExon 1: 182,589,167–182,589,256, 90 bases76543215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.2 kb of the gene's 15.6 kb; 2,226 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Human Phenotype Ontology, release 2026-09-01: the traits linked to the gene. Find out more at hpo.jax.org.

Cite this page

APA

Dante Labs. (n.d.). RNASEL gene: ribonuclease L. Retrieved 17 October 2026, from https://dantelabs.com/genes/rnasel

Vancouver

Dante Labs. RNASEL gene: ribonuclease L [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/rnasel

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