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Gene

PTPRB

protein tyrosine phosphatase receptor type B

Summary

Cytogenetic location
12q15
Coordinates
Chromosome 12: 70,515,870–70,637,429 (GRCh38)
Exons
34 exons across 121.6 kb
Protein
2,215 amino acids
Previous symbols
PTPB
MANE Select transcript
ENST00000334414.11NM_001109754.4
Locus type
gene with protein product

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PTPRB yet. The test sequences your whole genome, so your data includes it all the same.

How PTPRB is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where PTPRB sits. PTPRB and 3 genes near it on chromosome 12, from 70,076,650 to 71,076,649.Chromosome 1212q15p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3370.2 Mb70.4 Mb70.6 Mb70.8 Mb71 MbCNOT2: 70,242,981–70,354,993, forward strandCNOT2KCNMB4: 70,366,204–70,434,292, forward strandKCNMB4PTPRB: 70,515,870–70,637,429, reverse strandPTPRBPTPRR: 70,638,067–70,920,842, reverse strandPTPRRDiagram of PTPRB: 34 exons on the reverse strand of chromosome 12Exon 34: 70,515,870–70,521,511, 5,642 basesExon 33: 70,524,471–70,524,591, 121 basesExon 32: 70,532,035–70,532,170, 136 basesExon 31: 70,534,488–70,534,651, 164 basesExon 30: 70,534,833–70,534,955, 123 basesExon 29: 70,536,025–70,536,159, 135 basesExon 28: 70,538,155–70,538,231, 77 basesExon 27: 70,538,924–70,539,014, 91 basesExon 26: 70,539,625–70,539,706, 82 basesExon 25: 70,539,827–70,539,844, 18 basesExon 24: 70,539,939–70,540,022, 84 basesExon 23: 70,540,858–70,540,957, 100 basesExon 22: 70,544,557–70,544,663, 107 basesExon 21: 70,552,777–70,553,020, 244 basesExon 20: 70,555,160–70,555,309, 150 basesExon 19: 70,555,870–70,556,148, 279 basesExon 18: 70,559,343–70,559,624, 282 basesExon 17: 70,560,671–70,560,934, 264 basesExon 16: 70,562,844–70,563,107, 264 basesExon 15: 70,566,435–70,566,704, 270 basesExon 14: 70,569,675–70,569,938, 264 basesExon 13: 70,571,026–70,571,289, 264 basesExon 12: 70,571,824–70,572,087, 264 basesExon 11: 70,576,382–70,576,645, 264 basesExon 10: 70,581,036–70,581,302, 267 basesExon 9: 70,587,007–70,587,267, 261 basesExon 8: 70,589,964–70,590,233, 270 basesExon 7: 70,592,282–70,592,545, 264 basesExon 6: 70,594,467–70,594,724, 258 basesExon 5: 70,596,049–70,596,327, 279 basesExon 4: 70,609,069–70,609,339, 271 basesExon 3: 70,622,390–70,622,646, 257 basesExon 2: 70,635,671–70,636,066, 396 basesExon 1: 70,637,341–70,637,429, 89 bases343025201510515′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 12.3 kb of the gene's 121.6 kb; 6,648 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PTPRB gene: protein tyrosine phosphatase receptor type B. Retrieved 17 October 2026, from https://dantelabs.com/genes/ptprb

Vancouver

Dante Labs. PTPRB gene: protein tyrosine phosphatase receptor type B [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/ptprb

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