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Gene

PLEKHO2

pleckstrin homology domain containing O2

Summary

Cytogenetic location
15q22.31
Coordinates
Chromosome 15: 64,841,915–64,868,002 (GRCh38)
Exons
6 exons across 26.1 kb
Protein
490 amino acids
Also known as
DKFZp761K2312, PP1628, pp9099
Previous symbols
PLEKHQ1
MANE Select transcript
ENST00000323544.5NM_025201.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads PLEKHO2 yet. The test sequences your whole genome, so your data includes it all the same.

How PLEKHO2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 15, with a bracket where PLEKHO2 sits. PLEKHO2 and 21 genes near it on chromosome 15, from 64,354,959 to 65,354,958.Chromosome 1515q22.31p13p12p11.2p11.1q11.1q11.2q12q13.1q13.2q13.3q14q15.1q15.2q15.3q21.1q21.2q21.3q22.1q22.2q22.31q22.32q22.33q23q24.1q24.2q24.3q25.1q25.2q25.3q26.1q26.2q26.364.4 Mb64.6 Mb64.8 Mb65 Mb65.2 MbCSNK1G1: 64,165,525–64,356,554, reverse strandCSNK1G1: 64,181,180–64,381,440, reverse strandPCLAF: 64,364,129–64,387,687, reverse strandPCLAFTRIP4: 64,387,748–64,458,653, forward strandTRIP4ZNF609: 64,460,549–64,686,068, forward strandZNF609OAZ2: 64,686,833–64,703,281, reverse strandOAZ2RBPMS2: 64,739,886–64,775,860, reverse strandRBPMS2PIF1: 64,815,629–64,825,677, reverse strandPIF1: 64,841,883–64,930,920, forward strandPLEKHO2: 64,841,915–64,868,002, forward strandPLEKHO2ANKDD1A: 64,911,853–64,979,845, forward strandANKDD1ASPG21: 64,954,566–64,990,312, reverse strandSPG21MTFMT: 64,990,829–65,029,652, reverse strandMTFMTSLC51B: 65,045,132–65,053,397, forward strandSLC51BRASL12: 65,053,337–65,076,690, reverse strandRASL12KBTBD13: 65,076,746–65,079,948, forward strandKBTBD13UBAP1L: 65,091,766–65,115,200, reverse strandUBAP1LPDCD7: 65,117,379–65,133,836, reverse strandPDCD7CLPX: 65,148,219–65,185,643, reverse strandCLPXCILP: 65,194,760–65,211,491, reverse strandCILPPARP16: 65,231,398–65,300,618, reverse strandPARP16IGDCC3: 65,327,127–65,378,087, reverse strandIGDCC3Diagram of PLEKHO2: 6 exons on the forward strand of chromosome 15Exon 1: 64,841,915–64,842,028, 114 basesExon 2: 64,848,593–64,848,742, 150 basesExon 3: 64,854,921–64,855,037, 117 basesExon 4: 64,859,894–64,859,998, 105 basesExon 5: 64,861,477–64,861,575, 99 basesExon 6: 64,864,899–64,868,002, 3,104 bases1234565′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 3.7 kb of the gene's 26.1 kb; 1,473 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). PLEKHO2 gene: pleckstrin homology domain containing O2. Retrieved 17 October 2026, from https://dantelabs.com/genes/plekho2

Vancouver

Dante Labs. PLEKHO2 gene: pleckstrin homology domain containing O2 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/plekho2

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