Variants

PALB2 variants

Predicted effect: Synonymous. 2 of the 552 PALB2 variants with a page here, most review stars first. Each page describes ClinVar's public record of the variant, never a result.

All552
Frameshift305
Nonsense (stop gained)190
Splice site or region50
Start lost4
Missense1
Synonymous2

Variant	Exon or intron	Position (GRCh38)	ClinVar classification	Review status
c.2559C>T	Exon 6	23,629,231	Likely pathogenic	3 stars out of 4 reviewed by expert panel
c.18G>T	Exon 1	23,641,140	Pathogenic/likely pathogenic	2 stars out of 4 criteria provided, multiple submitters, no conflicts