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Gene

OSBP2

oxysterol binding protein 2

Summary

Cytogenetic location
22q12.2
Coordinates
Chromosome 22: 30,694,874–30,907,813 (GRCh38)
Exons
14 exons across 212.9 kb
Protein
916 amino acids
Also known as
KIAA1664, ORP-4, ORP4
Previous symbols
OSBPL1
MANE Select transcript
ENST00000332585.11NM_030758.4
Locus type
Protein-coding
  • Very high
  • Confident
  • Low
  • Very low

Curated reports relevant to this gene

No Genome Test report reads OSBP2 yet. The test sequences your whole genome, so your data includes it all the same.

How OSBP2 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 22, with a bracket where OSBP2 sits. OSBP2 and 24 genes near it on chromosome 22, from 30,301,344 to 31,301,343.Chromosome 2222q12.2p13p12p11.2p11.1q11.1q11.21q11.22q11.23q12.1q12.2q12.3q13.1q13.2q13.31q13.32q13.3330.4 Mb30.6 Mb30.8 Mb31 Mb31.2 MbTBC1D10A: 30,291,990–30,326,947, reverse strandTBC1D10ASF3A1: 30,331,988–30,356,919, reverse strandSF3A1CCDC157: 30,356,631–30,378,673, forward strandCCDC157RNF215: 30,368,811–30,421,771, reverse strandSEC14L2: 30,396,941–30,425,303, forward strandSEC14L2: 30,409,255–30,428,990, forward strandMTFP1: 30,425,623–30,429,058, forward strandMTFP1SEC14L3: 30,447,959–30,472,056, reverse strandSEC14L3SEC14L4: 30,488,890–30,505,725, reverse strandSEC14L4SEC14L6: 30,522,799–30,546,741, reverse strandSEC14L6GAL3ST1: 30,554,632–30,576,210, reverse strandGAL3ST1PES1: 30,576,624–30,607,083, reverse strandPES1TCN2: 30,607,003–30,630,712, forward strandTCN2SLC35E4: 30,635,673–30,669,016, forward strandSLC35E4DUSP18: 30,652,051–30,667,887, reverse strandDUSP18OSBP2: 30,694,874–30,907,813, forward strandOSBP2MORC2: 30,925,130–30,969,662, reverse strandMORC2TUG1: 30,969,245–30,979,413, forward strandTUG1SMTN: 31,064,105–31,104,757, forward strandSMTNSELENOM: 31,104,772–31,120,069, reverse strandSELENOMINPP5J: 31,122,731–31,134,697, forward strandINPP5JPLA2G3: 31,130,768–31,140,513, reverse strandPLA2G3RNF185: 31,160,149–31,207,019, forward strandRNF185LIMK2: 31,212,193–31,280,964, forward strandLIMK2PIK3IP1: 31,281,594–31,292,544, reverse strandPIK3IP1Diagram of OSBP2: 14 exons on the forward strand of chromosome 22Exon 1: 30,694,874–30,695,553, 680 basesExon 2: 30,741,161–30,741,369, 209 basesExon 3: 30,870,429–30,870,682, 254 basesExon 4: 30,887,426–30,887,618, 193 basesExon 5: 30,888,223–30,888,340, 118 basesExon 6: 30,889,177–30,889,234, 58 basesExon 7: 30,889,490–30,889,636, 147 basesExon 8: 30,890,728–30,890,973, 246 basesExon 9: 30,893,122–30,893,242, 121 basesExon 10: 30,893,463–30,893,566, 104 basesExon 11: 30,893,638–30,893,733, 96 basesExon 12: 30,893,817–30,894,001, 185 basesExon 13: 30,905,837–30,906,069, 233 basesExon 14: 30,906,197–30,907,813, 1,617 bases1510145′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.3 kb of the gene's 212.9 kb; 2,751 of those bases code for the protein.

Sequencing OSBP2

4Easy

How hard OSBP2 is to sequence with short reads, out of 100

Almost all of OSBP2's exons sit where short reads map cleanly.

What adds to it: the share of OSBP2's exons in each kind of hard region

  • Mappability0%
  • Homology0%
  • Repeats5.2%
  • GC content33%
  • Reference coverage0%

A Dante Labs score from our own research, built on NIST's Genome in a Bottle maps of hard-to-sequence regions.How it's scored

External links

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.
  • The Genome in a Bottle genome stratifications, from NIST: the sequencing difficulty score.

Cite this page

APA

Dante Labs. (n.d.). OSBP2 gene: oxysterol binding protein 2. Retrieved 18 October 2026, from https://dantelabs.com/genes/osbp2

Vancouver

Dante Labs. OSBP2 gene: oxysterol binding protein 2 [Internet]. [cited 18 October 2026]. Available from: https://dantelabs.com/genes/osbp2

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