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Gene

MAP3K6

mitogen-activated protein kinase kinase kinase 6

Summary

Cytogenetic location
1p36.11
Coordinates
Chromosome 1: 27,355,184–27,366,961 (GRCh38)
Exons
29 exons across 11.8 kb
Protein
1,288 amino acids
Also known as
MAPKKK6, ASK2, MEKK6
MANE Select transcript
ENST00000357582.3NM_004672.5
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MAP3K6 yet. The test sequences your whole genome, so your data includes it all the same.

How MAP3K6 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
Chromosome 1, with a bracket where MAP3K6 sits. MAP3K6 and 22 genes near it on chromosome 1, from 26,861,073 to 27,861,072.Chromosome 11p36.11p36.33p36.32p36.31p36.23p36.22p36.21p36.13p36.12p36.11p35.3p35.2p35.1p34.3p34.2p34.1p33p32.3p32.2p32.1p31.3p31.2p31.1p22.3p22.2p22.1p21.3p21.2p21.1p13.3p13.2p13.1p12p11.2p11.1q11q12q21.1q21.2q21.3q22q23.1q23.2q23.3q24.1q24.2q24.3q25.1q25.2q25.3q31.1q31.2q31.3q32.1q32.2q32.3q41q42.11q42.12q42.13q42.2q42.3q43q4427 Mb27.2 Mb27.4 Mb27.6 Mb27.8 MbSFN: 26,863,149–26,864,456, forward strandSFNGPN2: 26,876,132–26,890,283, reverse strandGPN2GPATCH3: 26,890,488–26,900,478, reverse strandGPATCH3NUDC: 26,900,238–26,946,886, forward strandNUDCNR0B2: 26,911,484–26,914,073, reverse strandNR0B2KDF1: 26,949,556–26,960,788, reverse strandKDF1TRNP1: 26,993,649–27,002,812, forward strandTRNP1TENT5B: 27,000,133–27,012,884, reverse strandTENT5BSLC9A1: 27,098,809–27,166,981, reverse strandSLC9A1WDTC1: 27,233,776–27,308,715, forward strandWDTC1TMEM222: 27,322,139–27,336,401, forward strandSYTL1: 27,342,009–27,353,937, forward strandSYTL1MAP3K6: 27,355,184–27,366,961, reverse strandMAP3K6FCN3: 27,369,108–27,374,920, reverse strandFCN3CD164L2: 27,379,176–27,383,339, reverse strandCD164L2GPR3: 27,392,614–27,395,814, forward strandWASF2: 27,404,226–27,490,308, reverse strandWASF2AHDC1: 27,534,035–27,604,431, reverse strandAHDC1FGR: 27,611,388–27,635,565, reverse strandFGRIFI6: 27,666,064–27,672,212, reverse strandIFI6FAM76A: 27,725,946–27,763,118, forward strandFAM76ASTX12: 27,773,153–27,824,450, forward strandSTX12PPP1R8: 27,830,763–27,851,676, forward strandPPP1R8Diagram of MAP3K6: 29 exons on the reverse strand of chromosome 1Exon 29: 27,355,184–27,355,469, 286 basesExon 28: 27,355,669–27,355,745, 77 basesExon 27: 27,356,026–27,356,099, 74 basesExon 26: 27,356,388–27,356,500, 113 basesExon 25: 27,356,590–27,356,749, 160 basesExon 24: 27,357,009–27,357,114, 106 basesExon 23: 27,357,400–27,357,576, 177 basesExon 22: 27,357,711–27,357,876, 166 basesExon 21: 27,358,181–27,358,319, 139 basesExon 20: 27,358,419–27,358,611, 193 basesExon 19: 27,358,709–27,358,866, 158 basesExon 18: 27,359,417–27,359,522, 106 basesExon 17: 27,359,858–27,359,994, 137 basesExon 16: 27,360,241–27,360,368, 128 basesExon 15: 27,360,705–27,360,838, 134 basesExon 14: 27,360,921–27,361,008, 88 basesExon 13: 27,361,157–27,361,252, 96 basesExon 12: 27,361,346–27,361,395, 50 basesExon 11: 27,361,520–27,361,627, 108 basesExon 10: 27,361,705–27,361,867, 163 basesExon 9: 27,362,091–27,362,250, 160 basesExon 8: 27,362,641–27,362,753, 113 basesExon 7: 27,362,851–27,363,021, 171 basesExon 6: 27,363,442–27,363,548, 107 basesExon 5: 27,363,917–27,364,085, 169 basesExon 4: 27,364,204–27,364,394, 191 basesExon 3: 27,364,661–27,364,684, 24 basesExon 2: 27,364,773–27,364,912, 140 basesExon 1: 27,366,258–27,366,961, 704 bases2928262422201816141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.4 kb of the gene's 11.8 kb; 3,867 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). MAP3K6 gene: mitogen-activated protein kinase kinase kinase 6. Retrieved 17 October 2026, from https://dantelabs.com/genes/map3k6

Vancouver

Dante Labs. MAP3K6 gene: mitogen-activated protein kinase kinase kinase 6 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/map3k6

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