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Gene

MAP3K12

mitogen-activated protein kinase kinase kinase 12

Summary

Cytogenetic location
12q13.13
Coordinates
Chromosome 12: 53,479,669–53,499,458 (GRCh38)
Exons
14 exons across 19.8 kb
Protein
892 amino acids
Also known as
MUK, DLK, ZPKP1, MEKK12
Previous symbols
ZPK
MANE Select transcript
ENST00000547488.6NM_001193511.2
Locus type
gene with protein product
  • Very high
  • Confident
  • Low
  • Very low

Reference genomeGRCh38

Positions on gene and variant pages follow this choice, in this browser.

Curated reports relevant to this gene

No Genome Test report reads MAP3K12 yet. The test sequences your whole genome, so your data includes it all the same.

How MAP3K12 is laid out

  • Coding sequence
  • Untranslated region
  • Intron
  • Direction of transcription
  • Stretches short reads find hard
Chromosome 12, with a bracket where MAP3K12 sits. MAP3K12 and 31 genes near it on chromosome 12, from 52,989,564 to 53,989,563.Chromosome 1212q13.13p13.33p13.32p13.31p13.2p13.1p12.3p12.2p12.1p11.23p11.22p11.21p11.1q11q12q13.11q13.12q13.13q13.2q13.3q14.1q14.2q14.3q15q21.1q21.2q21.31q21.32q21.33q22q23.1q23.2q23.3q24.11q24.12q24.13q24.21q24.22q24.23q24.31q24.32q24.3353 Mb53.2 Mb53.4 Mb53.6 Mb53.8 MbEIF4B: 53,006,263–53,042,230, forward strandEIF4BTNS2: 53,046,969–53,064,621, forward strandTNS2SPRYD3: 53,064,316–53,079,414, reverse strandSPRYD3IGFBP6: 53,097,436–53,102,345, forward strandIGFBP6SOAT2: 53,103,457–53,124,538, forward strandSOAT2CSAD: 53,157,663–53,180,933, reverse strandCSADZNF740: 53,180,555–53,195,142, forward strandZNF740ITGB7: 53,191,318–53,207,310, reverse strandITGB7RARG: 53,210,566–53,232,980, reverse strandRARG: 53,241,900–53,242,722, forward strandSLC61A1: 53,251,251–53,254,406, forward strandSLC61A1ESPL1: 53,268,248–53,293,643, forward strandESPL1PFDN5: 53,295,291–53,299,455, forward strandPFDN5MYG1: 53,299,695–53,307,181, forward strandMYG1AAAS: 53,307,456–53,324,864, reverse strandAAASSP7: 53,326,575–53,345,315, reverse strandSP7SP1: 53,380,135–53,416,446, forward strandSP1AMHR2: 53,423,672–53,431,672, forward strandAMHR2PRR13: 53,441,308–53,446,660, forward strandPRR13PCBP2: 53,451,900–53,484,618, forward strandPCBP2MAP3K12: 53,479,669–53,499,458, reverse strandMAP3K12TARBP2: 53,500,921–53,506,431, forward strandTARBP2NPFF: 53,506,684–53,507,491, reverse strandNPFFATF7-NPFF: 53,506,691–53,625,979, reverse strandATF7-NPFFATF7: 53,507,856–53,626,412, reverse strandATP5MC2: 53,626,515–53,678,658, reverse strandATP5MC2CALCOCO1: 53,708,517–53,727,745, reverse strandCALCOCO1HOXC13: 53,938,718–53,946,544, forward strandHOXC13HOXC12: 53,954,903–53,958,956, forward strandHOXC12HOXC11: 53,973,126–53,977,643, forward strandHOXC11HOXC10: 53,985,065–53,990,279, forward strandHOXC10: 53,985,845–54,034,888, forward strandDiagram of MAP3K12: 14 exons on the reverse strand of chromosome 12Exon 14: 53,479,669–53,481,280, 1,612 basesExon 13: 53,481,941–53,482,211, 271 basesExon 12: 53,482,299–53,482,369, 71 basesExon 11: 53,482,565–53,483,189, 625 basesExon 10: 53,483,349–53,483,486, 138 basesExon 9: 53,483,607–53,483,723, 117 basesExon 8: 53,483,911–53,484,020, 110 basesExon 7: 53,484,257–53,484,365, 109 basesExon 6: 53,485,056–53,485,214, 159 basesExon 5: 53,485,317–53,485,475, 159 basesExon 4: 53,486,056–53,486,247, 192 basesExon 3: 53,486,439–53,486,622, 184 basesExon 2: 53,486,947–53,487,428, 482 basesExon 1: 53,499,427–53,499,458, 32 bases141210864215′3′

Exons of the gene's MANE Select transcript (release v1.5), from NCBI and EMBL-EBI, on the GRCh38 reference genome.

Chromosome bands from UCSC's GRCh38 ideogram (2022-10-29).

Nearby genes from Ensembl release 116, on GRCh38.

Exons make up 4.3 kb of the gene's 19.8 kb; 2,679 of those bases code for the protein.

Where this comes from

  • HGNC: the gene's symbol, name, other symbols and location.
  • MANE Select v1.5, from NCBI and EMBL-EBI: the transcript, its exons and coding sequence.

Cite this page

APA

Dante Labs. (n.d.). MAP3K12 gene: mitogen-activated protein kinase kinase kinase 12. Retrieved 17 October 2026, from https://dantelabs.com/genes/map3k12

Vancouver

Dante Labs. MAP3K12 gene: mitogen-activated protein kinase kinase kinase 12 [Internet]. [cited 17 October 2026]. Available from: https://dantelabs.com/genes/map3k12

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